Database & User Guide
Detailed information about ProtHub's data construction and instructions for analysis tools.
Database Construction
ProtHub is a comprehensive platform designed for proteomic data integration and eHit generation. Our database is built upon the Human Proteome (UP000005640), integrating structural data from AlphaFold and PDB, along with bioactivity data from ChEMBL.
Function Guide
UniProt Search
Allows users to search for specific proteins using UniProt ID (e.g., P00533) or Gene Name (e.g., EGFR). The system provides a real-time autocomplete feature for quick access to target dashboards.
Sequence Search (BLAST)
Perform a sequence alignment search against our database. Input your protein sequence in FASTA format to identify homologous proteins and retrieve related ligand information.
Similarity Search
Search for ligands with similar chemical structures using SMILES codes. Calculates Tanimoto similarity scores to identify potential binders across the human proteome.
AI Predictor
Utilizes deep learning models to predict the bioactivity of a given chemical structure against specific protein targets. Useful for virtual screening and hit discovery.
Contact Us
중앙대학교 102관 (약학대학 / R&D 센터) 612호
Building 102 (#612)
Email: yoonjilee@cau.ac.kr