Q9Y6M4 | KC1G3_HUMAN | Casein kinase I isoform gamma-3 (CSNK1G3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 44~259 | |
| PF12605 | CK1gamma_C - Casein kinase 1 gamma C terminal | 328~417 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4101902 |  |
IC50 | = | 460.0 | nM | 429.46 | Cn1nc(-c2cnc(N)c(-c3ccc(C(N)=O)c(F)c3)n2)nc1C1(c2ccccc2)CC1 | Homo sapiens | CHEMBL4001602 | assay format |
| CHEMBL4744428 |  |
IC50 | <= | 500.0 | nM | 433.52 | CC(C)n1cnnc1-c1cccc(NC(=O)[C@H]2CN(c3ccc(C4CC4)nc3)CCO2)n1 | Homo sapiens | CHEMBL4727568 | single protein format |
| CHEMBL3337846 |  |
IC50 | = | 800.0 | nM | 347.28 | COc1cccc(C(=O)Nc2nc3cc4c(cc3[nH]2)OC(F)(F)O4)c1 | Homo sapiens | CHEMBL3386216 | assay format |
| CHEMBL3337845 |  |
IC50 | = | 810.0 | nM | 527.39 | O=C(Nc1nc2cc3c(cc2[nH]1)OC(F)(F)O3)c1csc(NC(=O)c2ccccc2OC(F)(F)F)n1 | Homo sapiens | CHEMBL3386216 | assay format |