Q9Y6L7 | TLL2_HUMAN | Tolloid-like protein 2 (TLL2)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00431 | CUB | 351–460 | |
| PF00431 | CUB | 464–573 | |
| PF00431 | CUB | 620–729 | |
| PF00431 | CUB | 776–884 | |
| PF00431 | CUB | 889–1002 | |
| PF01400 | Astacin | 159–349 | |
| PF07645 | EGF_CA | 732–771 | |
| PF14670 | FXa_inhibition | 584–616 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4207308 |  |
IC50 | = | 160.0 | nM | 429.52 | CCCCC[C@@H](C(=O)NCNC(=O)c1ccc(-c2ccccc2)o1)[C@@H](CC)N(O)C=O | Homo sapiens | CHEMBL4199882 | cell-based format |
| CHEMBL4214046 |  |
Ki | = | 0.26 | nM | 553.55 | CCCCC[C@@H](C(=O)NCNC(=O)c1ccc(-c2cc(OCC)cc(P(=O)(O)O)c2)o1)[C@@H](CC)N(O)C=O | Homo sapiens | CHEMBL4199904 | single protein format |