Q9Y6K0 | CEPT1_HUMAN | Choline/ethanolaminephosphotransferase 1 (CEPT1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01066 | CDP-OH_P_transf - CDP-alcohol phosphatidyltransferase | 82~235 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL593709 |  |
IC50 | = | 28.0 | nM | 441.49 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(C#N)cc(C(C)(C)O)c3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL596491 |  |
IC50 | = | 31.0 | nM | 455.51 | CCC(C)(O)c1cc(C#N)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL595357 |  |
IC50 | = | 44.0 | nM | 495.37 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(Br)cc(C(C)(C)O)c3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL595352 |  |
IC50 | = | 46.0 | nM | 427.46 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(C#N)cc(C(C)O)c3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL596476 |  |
IC50 | = | 58.0 | nM | 469.54 | CCCC(C)(O)c1cc(C#N)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL596490 |  |
IC50 | = | 59.0 | nM | 481.35 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(Br)cc(C(C)O)c3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL596130 |  |
IC50 | = | 60.0 | nM | 397.43 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(C#N)cc(C)c3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL606349 |  |
IC50 | = | 62.0 | nM | 401.4 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(C#N)cc(F)c3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL594868 |  |
IC50 | = | 80.0 | nM | 469.54 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(C#N)cc(C(C)(O)C(C)C)c3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL595359 |  |
IC50 | = | 86.0 | nM | 425.44 | CC(=O)c1cc(C#N)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL593247 |  |
IC50 | = | 94.0 | nM | 505.37 | C#CC(C)(O)c1cc(Br)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL606696 |  |
IC50 | = | 110.0 | nM | 509.4 | CCC(C)(O)c1cc(Br)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL260546 |  |
IC50 | = | 130.0 | nM | 383.41 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(C#N)ccc3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL592998 |  |
IC50 | = | 160.0 | nM | 465.51 | CC#CC(C)(O)c1cc(C#N)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL594183 |  |
IC50 | = | 200.0 | nM | 523.43 | CCCC(C)(O)c1cc(Br)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL593246 |  |
IC50 | = | 210.0 | nM | 523.43 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(Br)cc(C(C)(O)C(C)C)c3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL595358 |  |
IC50 | = | 210.0 | nM | 519.4 | CC#CC(C)(O)c1cc(Br)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL594978 |  |
IC50 | = | 270.0 | nM | 408.42 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3cc(C#N)cc(C#N)c3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL593007 |  |
IC50 | = | 380.0 | nM | 479.33 | CC(=O)c1cc(Br)cc2nc(-c3ccc(NC(=O)COc4ccccc4C)cc3)oc12 | Homo sapiens | CHEMBL1070006 | single protein format |
| CHEMBL596131 |  |
IC50 | = | 410.0 | nM | 383.41 | Cc1ccccc1OCC(=O)Nc1ccc(-c2nc3ccc(C#N)cc3o2)cc1 | Homo sapiens | CHEMBL1070006 | single protein format |