Q9Y6E0 | STK24_HUMAN | Serine/threonine-protein kinase 24 (STK24)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 36~286 | |
| PF20929 | PDCD10_N - Programmed cell death protein 10, dimerisation domain | 375~429 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL288441 |  |
IC50 | = | 3.9 | nM | 530.46 | COc1cc(Nc2c(C#N)cnc3cc(OCCCN4CCN(C)CC4)c(OC)cc23)c(Cl)cc1Cl | Homo sapiens | CHEMBL1244333 | single protein format |
| CHEMBL388978 |  |
IC50 | = | 4.32 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328515 | single protein format |
| CHEMBL3770443 |  |
IC50 | = | 43.0 | nM | 492.97 | CNc1ncc2cc(-c3ccc(-c4cccc(C)n4)cc3Cl)c(=O)n(C[C@H]3OC[C@H](N)CO3)c2n1 | Homo sapiens | CHEMBL3772528 | single protein format |
| CHEMBL4554938 |  |
IC50 | = | 44.8 | nM | 416.49 | CN1C(=O)c2sccc2N(C)c2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc21 | Homo sapiens | CHEMBL5212991 | single protein format |
| CHEMBL4580220 |  |
IC50 | = | 94.0 | nM | 468.54 | CCc1ccccc1C(=O)Nc1n[nH]c2c(C)c(F)c(C3C(C#N)=C(C)N(C)C(C)=C3C#N)cc12 | Homo sapiens | CHEMBL4884398 | single protein format |