Q9Y657 | SPIN1_HUMAN | Spindlin-1 (SPIN1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02513 | Spin-Ssty - Spin/Ssty Family | 54~102 | |
| PF02513 | Spin-Ssty - Spin/Ssty Family | 133~182 | |
| PF02513 | Spin-Ssty - Spin/Ssty Family | 214~259 |
3D structures mapped by conservation among orthologs
[ Domain: "SH3" // Spin-Ssty_1 ]
[ Domain: "SH3" // Spin-Ssty_2 ]
[ Domain: "SH3" // Spin-Ssty ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3109630 |  |
IC50 | = | 186.0 | nM | 329.44 | COc1cc2c(cc1OCCCN1CCCC1)N=C(N)C21CCC1 | Homo sapiens | CHEMBL4323125 | assay format |
| CHEMBL4552020 |  |
IC50 | = | 243.0 | nM | 341.46 | COc1c(CN)cc(CN)cc1OCCCN1Cc2ccccc2C1 | Homo sapiens | CHEMBL4377289 | cell-based format |
| CHEMBL4591023 |  |
IC50 | = | 340.0 | nM | 461.61 | COc1ccc2c(c1)CN(CCCOc1cc3c(cc1OCC1CC1)C1(CCCC1)C(N)=N3)C2 | Homo sapiens | CHEMBL4323097 | assay format |
| CHEMBL4528213 |  |
IC50 | = | 360.0 | nM | 405.54 | CC1(C)C(N)=Nc2cc(OCCCN3Cc4ccccc4C3)c(OCC3CC3)cc21 | Homo sapiens | CHEMBL4323097 | assay format |
| CHEMBL4476309 |  |
IC50 | = | 390.0 | nM | 431.58 | NC1=Nc2cc(OCCCN3Cc4ccccc4C3)c(OCC3CC3)cc2C12CCCC2 | Homo sapiens | CHEMBL4323097 | assay format |
| CHEMBL4518756 |  |
IC50 | = | 600.0 | nM | 421.54 | COc1ccc2c(c1)CN(CCCOc1cc3c(cc1OC)C1(CCCC1)C(N)=N3)C2 | Homo sapiens | CHEMBL4323097 | assay format |
| CHEMBL4569420 |  |
IC50 | = | 660.0 | nM | 391.52 | COc1cc2c(cc1OCCCN1Cc3ccccc3C1)N=C(N)C21CCCC1 | Homo sapiens | CHEMBL4323097 | assay format |
| CHEMBL4588285 |  |
IC50 | = | 741.0 | nM | 293.41 | COc1c(CN)cc(CN)cc1OCCCN1CCCC1 | Homo sapiens | CHEMBL4377289 | cell-based format |
| CHEMBL4458252 |  |
IC50 | = | 760.0 | nM | 343.47 | COc1cc2c(cc1OCCCN1CCCC1)N=C(N)C21CCCC1 | Homo sapiens | CHEMBL4323097 | assay format |