Q9Y4C1 | KDM3A_HUMAN | Lysine-specific demethylase 3A (KDM3A)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02373 | JmjC | 1155–1264 | |
| PF22987 | Tudor_KDM3B | 183–248 | |
| PF22988 | PWWP_KDM3B | 88–177 | |
| PF22989 | DUF7030 | 12–77 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3774692 |  |
IC50 | = | 57.0 | nM | 221.24 | Nc1nc(-c2cc(C(=O)O)ccn2)cs1 | Homo sapiens | CHEMBL3776390 | single protein format |
| CHEMBL3108958 |  |
IC50 | = | 140.0 | nM | 488.42 | N[C@@H]1C[C@H]1c1ccc(NC(=O)c2ccnc(-c3cc(C(=O)O)ccn3)c2)cc1.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL3110469 | single protein format |
| CHEMBL1230640 |  |
IC50 | = | 170.0 | nM | 189.17 | O=C(O)c1ccc(O)c2ncccc12 | Homo sapiens | CHEMBL3110469 | single protein format |
| CHEMBL5173876 |  |
IC50 | = | 400.0 | nM | 325.32 | O=C(O)/C=C/C(=O)NNC(=O)c1cnccc1Cc1ccccc1 | Homo sapiens | CHEMBL5216106 | single protein format |