Q9Y3Q0 | NALD2_HUMAN | N-acetylated-alpha-linked acidic dipeptidase 2 (NAALAD2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02225 | PA - PA domain | 161~249 | |
| PF04253 | TFR_dimer - Transferrin receptor-like dimerisation domain | 617~737 | |
| PF04389 | Peptidase_M28 - Peptidase family M28 | 347~550 |
3D structures mapped by conservation among orthologs
[ Domain: "Transferrin receptor ectodomain, C-terminal domain" // TFR_dimer ]
[ Domain: "Zn-dependent exopeptidases" // Peptidase_M28 ]
[ Domain: "The "swivelling" beta/beta/alpha domain" // PA ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL49669 |  |
Ki | = | 0.9 | nM | 344.28 | O=C(O)CC[C@H](NC(=O)N[C@@H](CCc1nnn[nH]1)C(=O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL47009 |  |
Ki | = | 1.4 | nM | 226.12 | O=C(O)CCC(CP(=O)(O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL298530 |  |
Ki | = | 2.1 | nM | 324.29 | O=C(O)CC[C@H](NC(=O)N[C@H](C(=O)O)c1ccccc1)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL297489 |  |
Ki | = | 3.0 | nM | 354.31 | O=C(O)CC[C@H](NC(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL47058 |  |
Ki | = | 5.3 | nM | 397.35 | N#CCCn1nnnc1CC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL50489 |  |
Ki | = | 5.9 | nM | 340.29 | O=C(O)CC[C@H](NC(=O)N[C@H](C(=O)O)c1ccc(O)cc1)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL46005 |  |
Ki | = | 8.0 | nM | 320.25 | O=C(O)CC[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL415916 |  |
Ki | = | 12.0 | nM | 338.32 | O=C(O)CC[C@H](NC(=O)N[C@@H](Cc1ccccc1)C(=O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL416650 |  |
Ki | = | 14.4 | nM | 334.28 | C[C@@H](C[C@H](NC(=O)N[C@@H](CCC(=O)O)C(=O)O)C(=O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL49271 |  |
Ki | = | 14.9 | nM | 368.31 | O=C(N[C@@H](CCc1nnn[nH]1)C(=O)O)N[C@@H](CCc1nnn[nH]1)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL47416 |  |
Ki | = | 95.3 | nM | 410.38 | O=C(O)CC[C@H](NC(=O)N[C@@H](C[C@@H](Cc1ccccc1)C(=O)O)C(=O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL3348570 |  |
Ki | = | 335.0 | nM | 344.28 | O=C(O)CC[C@H](NC(=O)N[C@@H](CCC(=O)O)C1N=NN=N1)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL295457 |  |
Ki | = | 392.0 | nM | 500.5 | O=C(N[C@@H](C[C@@H](Cc1ccccc1)C(=O)O)C(=O)O)N[C@@H](C[C@H](Cc1ccccc1)C(=O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |
| CHEMBL45640 |  |
Ki | = | 939.0 | nM | 348.31 | C[C@@](CCC(=O)O)(NC(=O)N[C@@](C)(CCC(=O)O)C(=O)O)C(=O)O | Homo sapiens | CHEMBL680921 | single protein format |