Q9Y2T6 | GPR55_HUMAN | G-protein coupled receptor 55 (GPR55)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 56~288 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2181542 |  |
IC50 | = | 113.0 | nM | 408.54 | CCCCCCCC(C)(C)c1cc(O)c2cc(Cc3ccccc3O)c(=O)oc2c1 | Homo sapiens | CHEMBL2388878 | cell-based format |
| CHEMBL2181540 |  |
IC50 | = | 261.0 | nM | 394.51 | CCCCCCC(C)(C)c1cc(O)c2cc(Cc3ccccc3O)c(=O)oc2c1 | Homo sapiens | CHEMBL2388878 | cell-based format |
| CHEMBL5273189 |  |
IC50 | = | 280.0 | nM | 410.54 | Cc1nc(N2CCN(C(=O)c3ccco3)CC2)c2c3c(sc2n1)CC(C)(C)CC3 | Homo sapiens | CHEMBL5225729 | cell-based format |
| CHEMBL2177264 |  |
IC50 | = | 358.0 | nM | 378.51 | CCCCCCC(C)(C)c1cc(O)c2cc(Cc3ccccc3)c(=O)oc2c1 | Homo sapiens | CHEMBL2388878 | cell-based format |
| CHEMBL3774473 |  |
IC50 | = | 420.0 | nM | 390.44 | O=C(N1CCC(n2nc(-c3cccnc3)oc2=O)CC1)C1(c2ccccc2)CC1 | Homo sapiens | CHEMBL3777631 | cell-based format |
| CHEMBL1484306 |  |
IC50 | = | 430.0 | nM | 396.52 | Cc1nc(N2CCN(C(=O)c3ccco3)CC2)c2c3c(sc2n1)CC(C)CC3 | Homo sapiens | CHEMBL5225731 | cell-based format |
| CHEMBL1567371 |  |
IC50 | = | 500.0 | nM | 527.61 | Cc1cc(C)c2nc(-c3cccnc3)cc(C(=O)Nc3ccc(S(=O)(=O)Nc4onc(C)c4C)cc3)c2c1 | Homo sapiens | CHEMBL5225737 | single protein format |
| CHEMBL1542168 |  |
IC50 | = | 640.0 | nM | 423.9 | O=C(N1CCC(n2nc(-c3ccccc3)oc2=O)CC1)C1(c2ccc(Cl)cc2)CC1 | Homo sapiens | CHEMBL3777631 | cell-based format |
| CHEMBL5273001 |  |
IC50 | = | 680.0 | nM | 368.46 | O=C(c1ccco1)N1CCN(c2ncnc3sc4c(c23)CCCC4)CC1 | Homo sapiens | CHEMBL5225729 | cell-based format |
| CHEMBL1402920 |  |
IC50 | = | 700.0 | nM | 382.49 | Cc1nc(N2CCN(C(=O)c3ccco3)CC2)c2c3c(sc2n1)CCCC3 | Homo sapiens | CHEMBL5225737 | single protein format |
| CHEMBL3775187 |  |
IC50 | = | 770.0 | nM | 431.54 | Cc1ccc(C2(C(=O)N3CCC(n4nc(-c5ccccc5)oc4=O)CC3)CC2(C)C)cc1 | Homo sapiens | CHEMBL3777631 | cell-based format |
| CHEMBL2181544 |  |
IC50 | = | 854.0 | nM | 392.5 | CCCCC1(c2cc(O)c3cc(Cc4ccccc4O)c(=O)oc3c2)CCCC1 | Homo sapiens | CHEMBL2388878 | cell-based format |
| CHEMBL1507657 |  |
IC50 | = | 860.0 | nM | 408.53 | O=C(c1ccco1)N1CCN(c2nc(C3CC3)nc3sc4c(c23)CCCC4)CC1 | Homo sapiens | CHEMBL5225731 | cell-based format |
| CHEMBL2181546 |  |
IC50 | = | 961.0 | nM | 406.52 | CCCCC1(c2cc(O)c3cc(Cc4ccccc4O)c(=O)oc3c2)CCCCC1 | Homo sapiens | CHEMBL2388878 | cell-based format |
| CHEMBL2387533 |  |
IC50 | = | 981.0 | nM | 338.4 | COc1ccccc1Cc1cc2c(C)c(OC)c(C)c(C)c2oc1=O | Homo sapiens | CHEMBL2388878 | cell-based format |