Q9Y2J8 | PADI2_HUMAN | Protein-arginine deiminase type-2 (PADI2)

Pfam Domain Table

AccessionDomainRangeColor
PF03068PAD - Protein-arginine deiminase (PAD)285~662
PF08526PAD_N - Protein-arginine deiminase (PAD) N-terminal domain1~114
PF08527PAD_M - Protein-arginine deiminase (PAD) middle domain116~274

3D structures mapped by conservation among orthologs

[ Domain: "Common fold of diphtheria toxin/transcription factors/cytochrome f" // PAD_M ]

 PyMOL session

[ Domain: "Cupredoxin-related" // PAD_N ]

 PyMOL session

[ Domain: "Pentein" // PAD ]

 PyMOL session


[ Alpha Fold Model ] (go)



Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL58150 IC50 = 200.0 nM 295.25 NC1=CC(=O)c2ccc(-c3cccc(C(=O)O)n3)nc2C1=O Homo sapiens CHEMBL3119094 single protein format
CHEMBL57818 IC50 = 320.0 nM 251.25 NC1=CC(=O)c2ccc(-c3ccccn3)nc2C1=O Homo sapiens CHEMBL3119094 single protein format
CHEMBL60908 IC50 = 740.0 nM 174.16 NC1=CC(=O)c2cccnc2C1=O Homo sapiens CHEMBL3119094 single protein format