Q9Y2D0 | CAH5B_HUMAN | Carbonic anhydrase 5B, mitochondrial (CA5B)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00194 | Carb_anhydrase - Eukaryotic-type carbonic anhydrase | 58~296 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5406311 |  |
Ki | = | 2.6 | nM | 524.41 | CC(=O)O[C@H]1[C@@H](OC(C)=O)[C@@H](CO)O[C@@H]([Se]c2ccc(S(N)(=O)=O)cc2)[C@@H]1OC(C)=O | Homo sapiens | CHEMBL5335409 | single protein format |
| CHEMBL5418256 |  |
Ki | = | 3.0 | nM | 517.42 | NS(=O)(=O)c1ccc(C(=O)Nc2ccc([Se][C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc2)cc1 | Homo sapiens | CHEMBL5335409 | single protein format |
| CHEMBL5433722 |  |
Ki | = | 4.2 | nM | 383.4 | NS(=O)(=O)c1ccc(S(=O)(=O)[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 | Homo sapiens | CHEMBL5335409 | single protein format |
| CHEMBL5420568 |  |
Ki | = | 5.5 | nM | 524.41 | CC(=O)O[C@@H]1[C@@H](OC(C)=O)[C@H]([Se]c2ccc(S(N)(=O)=O)cc2)O[C@H](CO)[C@H]1OC(C)=O | Homo sapiens | CHEMBL5335409 | single protein format |
| CHEMBL4163634 |  |
Ki | = | 5.5 | nM | 294.23 | COCC[Se]c1ccc(S(N)(=O)=O)cc1 | Homo sapiens | CHEMBL4149854 | single protein format |
| CHEMBL4165154 |  |
Ki | = | 5.7 | nM | 278.24 | CC(C)[Se]c1ccc(S(N)(=O)=O)cc1 | Homo sapiens | CHEMBL4149854 | single protein format |
| CHEMBL4159870 |  |
Ki | = | 5.7 | nM | 261.16 | N#C[Se]c1ccc(S(N)(=O)=O)cc1 | Homo sapiens | CHEMBL4149854 | single protein format |
| CHEMBL4161289 |  |
Ki | = | 5.7 | nM | 470.29 | NS(=O)(=O)c1ccc([Se][Se]c2ccc(S(N)(=O)=O)cc2)cc1 | Homo sapiens | CHEMBL4149854 | single protein format |
| CHEMBL5429492 |  |
Ki | = | 5.8 | nM | 477.51 | CC(=O)O[C@H]1[C@@H](OC(C)=O)[C@@H](CO)O[C@@H](Sc2ccc(S(N)(=O)=O)cc2)[C@@H]1OC(C)=O | Homo sapiens | CHEMBL5335409 | single protein format |
| CHEMBL574021 |  |
Ki | = | 5.9 | nM | 369.24 | NS(=O)(=O)c1ccc(NC(=O)Cc2ccccc2)c(Br)c1 | Homo sapiens | CHEMBL1046600 | single protein format |
| CHEMBL5418092 |  |
Ki | = | 6.0 | nM | 551.55 | CC(=O)OC[C@H]1O[C@@H](S(=O)(=O)c2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O | Homo sapiens | CHEMBL5335409 | single protein format |
| CHEMBL582841 |  |
Ki | = | 6.1 | nM | 298.35 | NS(=O)(=O)c1nnc(NC(=O)Cc2ccccc2)s1 | Homo sapiens | CHEMBL1046600 | single protein format |
| CHEMBL5439370 |  |
Ki | = | 6.2 | nM | 548.5 | NS(=O)(=O)c1ccc(NC(=S)Nc2ccc([Se][C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)cc2)cc1 | Homo sapiens | CHEMBL5335409 | single protein format |
| CHEMBL5439211 |  |
Ki | = | 6.6 | nM | 566.44 | CC(=O)OC[C@H]1O[C@@H]([Se]c2ccc(S(N)(=O)=O)cc2)[C@H](OC(C)=O)[C@@H](OC(C)=O)[C@H]1OC(C)=O | Homo sapiens | CHEMBL5335409 | single protein format |
| CHEMBL582965 |  |
Ki | = | 6.8 | nM | 291.33 | NS(=O)(=O)c1ccc(NC(=O)Cc2ccccn2)cc1 | Homo sapiens | CHEMBL1046600 | single protein format |
| CHEMBL573127 |  |
Ki | = | 7.0 | nM | 296.37 | NS(=O)(=O)c1ccc(NC(=O)Cc2cccs2)cc1 | Homo sapiens | CHEMBL1046600 | single protein format |
| CHEMBL574779 |  |
Ki | = | 7.2 | nM | 310.4 | NS(=O)(=O)c1ccc(CNC(=O)Cc2cccs2)cc1 | Homo sapiens | CHEMBL1046600 | single protein format |
| CHEMBL1683475 |  |
Ki | = | 7.3 | nM | 408.53 | Cn1nc(S(N)(=O)=O)s/c1=N\S(=O)(=O)C[C@]12CCC(CC1=O)C2(C)C | Homo sapiens | CHEMBL1686238 | single protein format |
| CHEMBL574780 |  |
Ki | = | 7.4 | nM | 304.38 | NS(=O)(=O)c1nnc(NC(=O)Cc2cccs2)s1 | Homo sapiens | CHEMBL1046600 | single protein format |
| CHEMBL5415949 |  |
Ki | = | 7.6 | nM | 548.5 | NS(=O)(=O)c1ccc(NC(=S)Nc2ccc([Se][C@@H]3O[C@H](CO)[C@H](O)[C@H](O)[C@H]3O)cc2)cc1 | Homo sapiens | CHEMBL5335409 | single protein format |