Q9Y263 | PLAP_HUMAN | Phospholipase A-2-activating protein (PLAA)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00400 | WD40 - WD domain, G-beta repeat | 58~97 | |
| PF00400 | WD40 - WD domain, G-beta repeat | 104~138 | |
| PF00400 | WD40 - WD domain, G-beta repeat | 142~178 | |
| PF00400 | WD40 - WD domain, G-beta repeat | 181~217 | |
| PF00400 | WD40 - WD domain, G-beta repeat | 221~258 | |
| PF00400 | WD40 - WD domain, G-beta repeat | 262~297 | |
| PF08324 | PUL - PUL domain | 535~789 | |
| PF09070 | PFU - PFU (PLAA family ubiquitin binding) | 346~458 |
3D structures mapped by conservation among orthologs
[ Domain: "ARM repeat" // PUL ]
[ Domain: "ubiquitin-binding domain from PLAA" // PFU ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1077979 |  |
IC50 | = | 11.0 | nM | 362.38 | COc1cc(O)c2c(c1)/C=C/C[C@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O | Homo sapiens | CHEMBL4024851 | single protein format |
| CHEMBL4068569 |  |
IC50 | = | 36.0 | nM | 380.37 | COc1cc(O)c2c(c1)/C=C/C[C@H](O)[C@H](O)C(=O)/C(F)=C\C[C@H](C)OC2=O | Homo sapiens | CHEMBL4024851 | single protein format |
| CHEMBL607856 |  |
IC50 | = | 800.0 | nM | 246.27 | CCc1nccn1CC(=O)c1ccc(O)c(O)c1 | Homo sapiens | CHEMBL1074487 | single protein format |
| CHEMBL608723 |  |
IC50 | = | 800.0 | nM | 268.27 | O=C(Cn1cnc2ccccc21)c1ccc(O)c(O)c1 | Homo sapiens | CHEMBL1074487 | single protein format |