Q9Y263 | PLAP_HUMAN | Phospholipase A-2-activating protein (PLAA)

Helixβ‑strandTurn secondary structure

Pfam Domain Table

AccessionDomainRangeColor
PF00400WD4058–97
PF00400WD40104–138
PF00400WD40142–178
PF00400WD40181–217
PF00400WD40221–258
PF00400WD40262–297
PF08324PUL535–789
PF09070PFU346–458

 3D structures mapped by conservation among orthologs

[ Domain: "ARM repeat" // PUL ]

 PyMOL session

[ Domain: "ubiquitin-binding domain from PLAA" // PFU ]

 PyMOL session


 [ Alpha Fold Model ] (go)



 Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL1077979 IC50 = 11.0 nM 362.38 COc1cc(O)c2c(c1)/C=C/C[C@H](O)[C@H](O)C(=O)/C=C\C[C@H](C)OC2=O Homo sapiens CHEMBL4024851 single protein format
CHEMBL4068569 IC50 = 36.0 nM 380.37 COc1cc(O)c2c(c1)/C=C/C[C@H](O)[C@H](O)C(=O)/C(F)=C\C[C@H](C)OC2=O Homo sapiens CHEMBL4024851 single protein format
CHEMBL607856 IC50 = 800.0 nM 246.27 CCc1nccn1CC(=O)c1ccc(O)c(O)c1 Homo sapiens CHEMBL1074487 single protein format
CHEMBL608723 IC50 = 800.0 nM 268.27 O=C(Cn1cnc2ccccc21)c1ccc(O)c(O)c1 Homo sapiens CHEMBL1074487 single protein format