Q9Y253 | POLH_HUMAN | DNA polymerase eta (POLH)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00817 | IMS - impB/mucB/samB family | 12~227 | |
| PF11799 | IMS_C - impB/mucB/samB family C-terminal domain | 316~429 | |
| PF18439 | zf_UBZ - Ubiquitin-Binding Zinc Finger | 631~661 | |
| PF21704 | POLH-Rev1_HhH - DNApol eta/Rev1, HhH motif | 250~305 |
3D structures mapped by conservation among orthologs
[ Domain: "SAM domain-like" // KOG2095_1st ]
- 3JAA
- 3MR2
- 3MR3
- 3MR5
- 3MR6
- 3SI8
- 3TQ1
- 4DL2
- 4DL3
- 4DL4
- 4DL5
- 4DL6
- 4DL7
- 4ECQ
- 4ECR
- 4ECS
- 4ECT
- 4ECU
- 4ECV
- 4ECW
- 4ECX
- 4ECY
- 4ECZ
- 4ED0
- 4ED1
- 4ED2
- 4ED3
- 4ED6
- 4ED7
- 4ED8
- 4EEY
- 4J9K
- 4J9L
- 4J9M
- 4J9N
- 4J9O
- 4J9P
- 4J9Q
- 4J9R
- 4J9S
- 4O3N
- 4O3O
- 4O3P
- 4O3Q
- 4O3R
- 4O3S
- 4Q8E
- 4Q8F
- 4RNM
- 4RNN
- 4RNO
- 4RU9
- 4YP3
- 4YQW
- 4YR0
- 4YR2
- 4YR3
- 5DG7
- 5DG8
- 5DG9
- 5DGA
- 5DGB
- 5DLF
- 5DLG
- 5DQG
- 5DQH
- 5DQI
- 5EWE
- 5EWF
- 5EWG
- 5F9L
- 5F9N
- 5JUM
- 5KFA
- 5KFB
- 5KFC
- 5KFD
- 5KFE
- 5KFF
- 5KFG
- 5KFH
- 5KFI
- 5KFJ
- 5KFK
- 5KFL
- 5KFM
- 5KFN
- 5KFO
- 5KFP
- 5KFQ
- 5KFR
- 5KFS
- 5KFT
- 5KFU
- 5KFV
- 5KFW
- 5KFX
- 5KFY
- 5KFZ
- 5KG0
- 5KG1
- 5KG2
- 5KG3
- 5KG4
- 5KG5
- 5KG6
- 5KG7
- 5L1I
- 5L1J
- 5L1K
- 5L1L
- 5L9X
- 6D0M
- 6D0Z
- 6M7O
- 6M7P
- 6M7T
- 6M7U
- 6M7V
- 6MP3
- 6MQ8
- 6MXO
- 6PZ3
- 6Q02
[ Domain: "Lesion bypass DNA polymerase (Y-family), little finger domain" // IMS_C ]
- 3JAA
- 3MR2
- 3MR3
- 3MR5
- 3MR6
- 3SI8
- 3TQ1
- 4DL2
- 4DL3
- 4DL4
- 4DL5
- 4DL6
- 4DL7
- 4ECQ
- 4ECR
- 4ECS
- 4ECT
- 4ECU
- 4ECV
- 4ECW
- 4ECX
- 4ECY
- 4ECZ
- 4ED0
- 4ED1
- 4ED2
- 4ED3
- 4ED6
- 4ED7
- 4ED8
- 4EEY
- 4J9K
- 4J9L
- 4J9M
- 4J9N
- 4J9O
- 4J9P
- 4J9Q
- 4J9R
- 4J9S
- 4O3N
- 4O3O
- 4O3P
- 4O3Q
- 4O3R
- 4O3S
- 4Q8E
- 4Q8F
- 4RNM
- 4RNN
- 4RNO
- 4RU9
- 4YP3
- 4YQW
- 4YR0
- 4YR2
- 4YR3
- 5DG7
- 5DG8
- 5DG9
- 5DGA
- 5DGB
- 5DLF
- 5DLG
- 5DQG
- 5DQH
- 5DQI
- 5EWE
- 5EWF
- 5EWG
- 5F9L
- 5F9N
- 5JUM
- 5KFA
- 5KFB
- 5KFC
- 5KFD
- 5KFE
- 5KFF
- 5KFG
- 5KFH
- 5KFI
- 5KFJ
- 5KFK
- 5KFL
- 5KFM
- 5KFN
- 5KFO
- 5KFP
- 5KFQ
- 5KFR
- 5KFS
- 5KFT
- 5KFU
- 5KFV
- 5KFW
- 5KFX
- 5KFY
- 5KFZ
- 5KG0
- 5KG1
- 5KG2
- 5KG3
- 5KG4
- 5KG5
- 5KG6
- 5KG7
- 5L1I
- 5L1J
- 5L1K
- 5L1L
- 5L9X
- 6D0M
- 6D0Z
- 6M7O
- 6M7P
- 6M7T
- 6M7U
- 6M7V
- 6MP3
- 6MQ8
- 6MXO
- 6PZ3
- 6Q02
[ Domain: "Adenylyl and guanylyl cyclase catalytic domain-like" // IMS ]
- 3JAA
- 3MR2
- 3MR3
- 3MR5
- 3MR6
- 3SI8
- 3TQ1
- 4DL2
- 4DL3
- 4DL4
- 4DL5
- 4DL6
- 4DL7
- 4ECQ
- 4ECR
- 4ECS
- 4ECT
- 4ECU
- 4ECV
- 4ECW
- 4ECX
- 4ECY
- 4ECZ
- 4ED0
- 4ED1
- 4ED2
- 4ED3
- 4ED6
- 4ED7
- 4ED8
- 4EEY
- 4J9K
- 4J9L
- 4J9M
- 4J9N
- 4J9O
- 4J9P
- 4J9Q
- 4J9R
- 4J9S
- 4O3N
- 4O3O
- 4O3P
- 4O3Q
- 4O3R
- 4O3S
- 4Q8E
- 4Q8F
- 4RNM
- 4RNN
- 4RNO
- 4RU9
- 4YP3
- 4YQW
- 4YR0
- 4YR2
- 4YR3
- 5DG7
- 5DG8
- 5DG9
- 5DGA
- 5DGB
- 5DLF
- 5DLG
- 5DQG
- 5DQH
- 5DQI
- 5EWE
- 5EWF
- 5EWG
- 5F9L
- 5F9N
- 5JUM
- 5KFA
- 5KFB
- 5KFC
- 5KFD
- 5KFE
- 5KFF
- 5KFG
- 5KFH
- 5KFI
- 5KFJ
- 5KFK
- 5KFL
- 5KFM
- 5KFN
- 5KFO
- 5KFP
- 5KFQ
- 5KFR
- 5KFS
- 5KFT
- 5KFU
- 5KFV
- 5KFW
- 5KFX
- 5KFY
- 5KFZ
- 5KG0
- 5KG1
- 5KG2
- 5KG3
- 5KG4
- 5KG5
- 5KG6
- 5KG7
- 5L1I
- 5L1J
- 5L1K
- 5L1L
- 5L9X
- 6D0M
- 6D0Z
- 6M7O
- 6M7P
- 6M7T
- 6M7U
- 6M7V
- 6MP3
- 6MQ8
- 6MXO
- 6PZ3
- 6Q02
[ Domain: "Hypothetical protein Ta1206-like" // IMS_1 ]
- 3JAA
- 3MR2
- 3MR3
- 3MR5
- 3MR6
- 3SI8
- 3TQ1
- 4DL2
- 4DL3
- 4DL4
- 4DL5
- 4DL6
- 4DL7
- 4ECQ
- 4ECR
- 4ECS
- 4ECT
- 4ECU
- 4ECV
- 4ECW
- 4ECX
- 4ECY
- 4ECZ
- 4ED0
- 4ED1
- 4ED2
- 4ED3
- 4ED6
- 4ED7
- 4ED8
- 4EEY
- 4J9K
- 4J9L
- 4J9M
- 4J9N
- 4J9O
- 4J9P
- 4J9Q
- 4J9R
- 4J9S
- 4O3N
- 4O3O
- 4O3P
- 4O3Q
- 4O3R
- 4O3S
- 4Q8E
- 4Q8F
- 4RNM
- 4RNN
- 4RNO
- 4RU9
- 4YP3
- 4YQW
- 4YR0
- 4YR2
- 4YR3
- 5DG7
- 5DG8
- 5DG9
- 5DGA
- 5DGB
- 5DLF
- 5DLG
- 5DQG
- 5DQH
- 5DQI
- 5EWE
- 5EWF
- 5EWG
- 5F9L
- 5F9N
- 5JUM
- 5KFA
- 5KFB
- 5KFC
- 5KFD
- 5KFE
- 5KFF
- 5KFG
- 5KFH
- 5KFI
- 5KFJ
- 5KFK
- 5KFL
- 5KFM
- 5KFN
- 5KFO
- 5KFP
- 5KFQ
- 5KFR
- 5KFS
- 5KFT
- 5KFU
- 5KFV
- 5KFW
- 5KFX
- 5KFY
- 5KFZ
- 5KG0
- 5KG1
- 5KG2
- 5KG3
- 5KG4
- 5KG5
- 5KG6
- 5KG7
- 5L1I
- 5L1J
- 5L1K
- 5L1L
- 5L9X
- 6D0M
- 6D0Z
- 6M7O
- 6M7P
- 6M7T
- 6M7U
- 6M7V
- 6MP3
- 6MQ8
- 6MXO
- 6PZ3
- 6Q02
[ Domain: "beta-beta-alpha zinc fingers" // KOG2095_2nd ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL6246 |  |
IC50 | = | 62.0 | nM | 302.19 | O=c1oc2c(O)c(O)cc3c(=O)oc4c(O)c(O)cc1c4c23 | Homo sapiens | CHEMBL3854639 | assay format |
| CHEMBL275938 |  |
IC50 | = | 75.0 | nM | 422.35 | O=C(O)C1=CC(=C(c2ccc(O)c(C(=O)O)c2)c2ccc(O)c(C(=O)O)c2)C=CC1=O | Homo sapiens | CHEMBL3854639 | assay format |