Q9UPY5 | XCT_HUMAN | Cystine/glutamate transporter (SLC7A11)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF13520 | AA_permease_2 - Amino acid permease | 48~457 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3629576 |  |
IC50 | = | 30.0 | nM | 589.09 | CC(=O)c1ccc(OC(C)C)c(-n2c(CN3CCN(C(=O)COc4ccc(Cl)cc4)CC3)nc3ccccc3c2=O)c1 | Homo sapiens | CHEMBL3631402 | cell-based format |
| CHEMBL3629575 |  |
IC50 | = | 60.0 | nM | 575.07 | CC(C)Oc1ccc(C=O)cc1-n1c(CN2CCN(C(=O)COc3ccc(Cl)cc3)CC2)nc2ccccc2c1=O | Homo sapiens | CHEMBL3631402 | cell-based format |
| CHEMBL421 |  |
IC50 | = | 160.0 | nM | 398.4 | O=C(O)c1cc(/N=N/c2ccc(S(=O)(=O)Nc3ccccn3)cc2)ccc1O | Homo sapiens | CHEMBL4331195 | single protein format |
| CHEMBL401989 |  |
IC50 | = | 200.0 | nM | 547.06 | CCOc1ccccc1-n1c(C(C)N2CCN(C(=O)COc3ccc(Cl)cc3)CC2)nc2ccccc2c1=O | Homo sapiens | CHEMBL3631402 | cell-based format |