Q9UNK4 | PA2GD_HUMAN | Group IID secretory phospholipase A2 (PLA2G2D)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00068 | Phospholip_A2_1 - Phospholipase A2 | 23~129 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL515637 |  |
IC50 | = | 7.0 | nM | 430.46 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |
| CHEMBL446349 |  |
IC50 | = | 35.0 | nM | 569.64 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |
| CHEMBL148674 |  |
IC50 | = | 60.0 | nM | 380.4 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |
| CHEMBL514705 |  |
IC50 | = | 80.0 | nM | 458.51 | CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |
| CHEMBL514841 |  |
IC50 | = | 80.0 | nM | 386.45 | CCc1c(C(=O)C(N)=O)c2c(OC)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |
| CHEMBL148649 |  |
IC50 | = | 120.0 | nM | 394.43 | CCc1c(C(=O)C(N)=O)c2c(OC(C)C(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |
| CHEMBL506485 |  |
IC50 | = | 170.0 | nM | 597.69 | CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |
| CHEMBL514692 |  |
IC50 | = | 170.0 | nM | 519.58 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |
| CHEMBL504813 |  |
IC50 | = | 500.0 | nM | 408.45 | CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |
| CHEMBL479251 |  |
IC50 | = | 700.0 | nM | 547.63 | CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990828 | assay format |