Q9ULW8 | PADI3_HUMAN | Protein-arginine deiminase type-3 (PADI3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF03068 | PAD - Protein-arginine deiminase (PAD) | 284~661 | |
| PF08526 | PAD_N - Protein-arginine deiminase (PAD) N-terminal domain | 1~113 | |
| PF08527 | PAD_M - Protein-arginine deiminase (PAD) middle domain | 115~273 |
3D structures mapped by conservation among orthologs
[ Domain: "Common fold of diphtheria toxin/transcription factors/cytochrome f" // PAD_M ]
[ Domain: "Cupredoxin-related" // PAD_N ]
[ Domain: "Pentein" // PAD,PAD_M ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL57818 |  |
IC50 | = | 130.0 | nM | 251.25 | NC1=CC(=O)c2ccc(-c3ccccn3)nc2C1=O | Homo sapiens | CHEMBL3119093 | single protein format |
| CHEMBL60908 |  |
IC50 | = | 170.0 | nM | 174.16 | NC1=CC(=O)c2cccnc2C1=O | Homo sapiens | CHEMBL3119093 | single protein format |
| CHEMBL3113470 |  |
IC50 | = | 390.0 | nM | 253.06 | NC1=C(Br)C(=O)c2cccnc2C1=O | Homo sapiens | CHEMBL3119093 | single protein format |
| CHEMBL11417 |  |
IC50 | = | 430.0 | nM | 506.47 | COC1=C(N)C(=O)c2nc(-c3nc(C(=O)O)c(C)c(-c4ccc(OC)c(OC)c4O)c3N)ccc2C1=O | Homo sapiens | CHEMBL3119093 | single protein format |
| CHEMBL1910971 |  |
IC50 | = | 690.0 | nM | 468.82 | N=C(CCl)NCCC[C@H](NC(=O)c1ccccc1C(=O)O)C(N)=O.O=C(O)C(F)(F)F | Homo sapiens | CHEMBL1914014 | single protein format |
| CHEMBL58150 |  |
IC50 | = | 710.0 | nM | 295.25 | NC1=CC(=O)c2ccc(-c3cccc(C(=O)O)n3)nc2C1=O | Homo sapiens | CHEMBL3119093 | single protein format |