Q9UL54 | TAOK2_HUMAN | Serine/threonine-protein kinase TAO2 (TAOK2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 29~281 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 11.7 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328626 | single protein format |
| CHEMBL4063500 |  |
IC50 | = | 84.0 | nM | 535.65 | CN(C)C(=O)c1cc2cnc(Nc3ccc(NC(=O)CCCCCCC(=O)NO)cc3)nc2n1C1CCCC1 | Homo sapiens | CHEMBL4024291 | cell-based format |
| CHEMBL2334586 |  |
IC50 | = | 89.0 | nM | 332.41 | CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 | Homo sapiens | CHEMBL5111451 | assay format |
| CHEMBL4554938 |  |
IC50 | = | 134.0 | nM | 416.49 | CN1C(=O)c2sccc2N(C)c2nc(Nc3ccc(S(N)(=O)=O)cc3)ncc21 | Homo sapiens | CHEMBL5212994 | single protein format |
| CHEMBL4568087 |  |
IC50 | = | 420.0 | nM | 421.53 | Cn1cc(-c2cnc3c(-c4csc(C(=O)N[C@@H]5CCCC[C@@H]5N)c4)cnn3c2)cn1 | Homo sapiens | CHEMBL4479784 | assay format |
| CHEMBL2006765 |  |
IC50 | = | 529.0 | nM | 392.39 | CCCNC(=O)c1ccc(Nc2nc(NCC(F)(F)F)c3cc[nH]c3n2)cc1 | Homo sapiens | CHEMBL4007749 | single protein format |
| CHEMBL5437375 |  |
IC50 | = | 689.0 | nM | 517.6 | Cc1ccc(Nc2nccc(N(C)c3ccc4c(C)n(C)nc4c3)n2)cc1-c1nc2c(C(N)=O)cccc2[nH]1 | Homo sapiens | CHEMBL5324554 | single protein format |
| CHEMBL4793380 |  |
IC50 | = | 903.0 | nM | 423.48 | CC(C)(C)c1cc(NC(=O)Nc2ccc(Nc3ncnc4c3OCCCN4)cc2)no1 | Homo sapiens | CHEMBL4767016 | single protein format |