Q9UKV8 | AGO2_HUMAN | Protein argonaute-2 (AGO2)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF02170 | PAZ | 242–365 | |
| PF02171 | Piwi | 518–817 | |
| PF08699 | ArgoL1 | 176–226 | |
| PF16486 | ArgoN | 36–166 | |
| PF16487 | ArgoMid | 429–510 | |
| PF16488 | ArgoL2 | 374–420 |
3D structures mapped by conservation among orthologs
[ Domain: "SH3" // PAZ ]
[ Domain: "Argonaute, N-terminal domain" // ArgoN ]
[ Domain: "Argonaute, N-terminal domain" // ArgoL1 ]
[ Domain: "Middle domain in Argonaute homologs" // Piwi_N_1 ]
[ Domain: "Ribonuclease H-like" // Piwi_C ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4439201 |  |
IC50 | = | 450.0 | nM | 424.36 | O=C(O)C1=CC(C(c2ccc(O)c(C(=O)O)c2)c2ccc(O)c(C(=O)O)c2)C=CC1=O | Homo sapiens | CHEMBL5233831 | single protein format |