Q9UKM7 | MA1B1_HUMAN | Endoplasmic reticulum mannosyl-oligosaccharide 1,2-alpha-mannosidase (MAN1B1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01532 | Glyco_hydro_47 - Glycosyl hydrolase family 47 | 257~695 |
3D structures mapped by conservation among orthologs
[ Domain: "alpha/alpha toroid" // Glyco_hydro_47 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2206824 |  |
Ki | = | 160.0 | nM | 434.33 | O=C(NC[C@H](NC[C@H]1NC[C@H](O)[C@@H]1O)c1ccccc1)c1ccccc1Br | Homo sapiens | CHEMBL2215204 | single protein format |
| CHEMBL2206818 |  |
Ki | = | 230.0 | nM | 342.44 | O[C@H]1[C@@H](O)CN[C@@H]1CN[C@@H](COCc1ccccc1)c1ccccc1 | Homo sapiens | CHEMBL2215204 | single protein format |
| CHEMBL2206823 |  |
Ki | = | 310.0 | nM | 437.33 | O[C@H]1[C@@H](O)CN[C@@H]1CN[C@@H](COCOc1ccc(Br)cc1)c1ccccc1 | Homo sapiens | CHEMBL2215204 | single protein format |
| CHEMBL2206822 |  |
Ki | = | 310.0 | nM | 437.33 | O[C@H]1[C@@H](O)CN[C@@H]1CN[C@@H](COCOc1cccc(Br)c1)c1ccccc1 | Homo sapiens | CHEMBL2215204 | single protein format |
| CHEMBL2206821 |  |
Ki | = | 440.0 | nM | 376.43 | O[C@H]1[C@@H](O)CN[C@@H]1CN[C@@H](COCOc1ccc(F)cc1)c1ccccc1 | Homo sapiens | CHEMBL2215204 | single protein format |
| CHEMBL2206819 |  |
Ki | = | 760.0 | nM | 360.43 | O[C@H]1[C@@H](O)CN[C@@H]1CN[C@@H](COCc1cccc(F)c1)c1ccccc1 | Homo sapiens | CHEMBL2215204 | single protein format |
| CHEMBL188227 |  |
Ki | = | 790.0 | nM | 328.41 | O[C@H]1[C@@H](O)CN[C@@H]1CN[C@H](c1ccccc1)[C@@H](O)c1ccccc1 | Homo sapiens | CHEMBL2215204 | single protein format |
| CHEMBL2206820 |  |
Ki | = | 910.0 | nM | 376.43 | O[C@H]1[C@@H](O)CN[C@@H]1CN[C@@H](COCOc1ccccc1F)c1ccccc1 | Homo sapiens | CHEMBL2215204 | single protein format |