Q9UIK4 | DAPK2_HUMAN | Death-associated protein kinase 2 (DAPK2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 23~285 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 7.25 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328381 | single protein format |
| CHEMBL3103192 |  |
IC50 | = | 10.0 | nM | 419.49 | CC(=O)Nc1cc(Nc2cc(NC3CC3)n3ncc(C#N)c3n2)ccc1N(C)CCN | Homo sapiens | CHEMBL3810712 | single protein format |
| CHEMBL4764610 |  |
IC50 | = | 22.0 | nM | 475.57 | COc1cc2c(=O)c3c4ccc(C#N)cc4[nH]c3n(C(C)C)c2c(F)c1N1C[C@@H](C)N(C)[C@@H](C)C1 | Homo sapiens | CHEMBL4705523 | single protein format |
| CHEMBL3799389 |  |
IC50 | = | 170.0 | nM | 360.37 | O=C1Nc2ccc(NC(=O)C3CC3)cc2/C1=C1/Nc2ccccc2/C1=N\O | Homo sapiens | CHEMBL3802097 | single protein format |
| CHEMBL3797466 |  |
IC50 | = | 570.0 | nM | 374.4 | CC(C)=CC(=O)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 | Homo sapiens | CHEMBL3802097 | single protein format |
| CHEMBL3799585 |  |
IC50 | = | 590.0 | nM | 362.39 | CCCC(=O)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 | Homo sapiens | CHEMBL3802097 | single protein format |
| CHEMBL513703 |  |
IC50 | = | 830.0 | nM | 376.42 | CC(C)(C)C(=O)Nc1ccc2c(c1)/C(=C1/Nc3ccccc3/C1=N\O)C(=O)N2 | Homo sapiens | CHEMBL3802097 | single protein format |