Q9UI32 | GLSL_HUMAN | Glutaminase liver isoform, mitochondrial (GLS2)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF04960 | Glutaminase | 177–463 | |
| PF12796 | Ank_2 | 490–575 | |
| PF17959 | EF-hand_14 | 73–155 |
3D structures mapped by conservation among orthologs
[ Domain: "Ankyrin repeat" // Ank_2 ]
[ Domain: "alpha-helical domain in beta-lactamase/transpeptidase-like proteins" // Glutaminase_2nd ]
[ Domain: "a+b domain in beta-lactamase/transpeptidase-like proteins" // Glutaminase_1st ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4452796 |  |
IC50 | = | 260.0 | nM | 382.54 | CCCCCCCCCCC[C@H](CC1=CC(O)C=C(OC)C1O)OC(C)=O | Homo sapiens | CHEMBL4422720 | single protein format |
| CHEMBL4552664 |  |
IC50 | = | 280.0 | nM | 406.56 | CCCCCCCCCCCCCC(CC1=CC(=O)C=C(OC)C1=O)OC(C)=O | Homo sapiens | CHEMBL4422720 | single protein format |
| CHEMBL4472618 |  |
IC50 | = | 290.0 | nM | 378.51 | CCCCCCCCCCC[C@H](CC1=CC(=O)C=C(OC)C1=O)OC(C)=O | Homo sapiens | CHEMBL4422720 | single protein format |