Q9UHF0 | TKNK_HUMAN | Tachykinin-3 (TAC3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF03823 | Neurokinin_B - Neurokinin B | 1~54 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3642160 |  |
IC50 | = | 23.0 | nM | 550.91 | CC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)c3ccc(Cl)cc3)C(c3ccc(Cl)c(Cl)c3)C2)CC1 | Homo sapiens | CHEMBL3707767 | cell-based format |
| CHEMBL3642157 |  |
IC50 | = | 24.0 | nM | 595.37 | CC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)c3ccc(Br)cc3)C(c3ccc(Cl)c(Cl)c3)C2)CC1 | Homo sapiens | CHEMBL3707767 | cell-based format |
| CHEMBL3642159 |  |
IC50 | = | 49.0 | nM | 530.5 | CC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)c3ccc(C)cc3)C(c3ccc(Cl)c(Cl)c3)C2)CC1 | Homo sapiens | CHEMBL3707767 | cell-based format |
| CHEMBL3642158 |  |
IC50 | = | 130.0 | nM | 546.5 | COc1ccc(C(=O)N(C)[C@@H]2CCN(C(=O)C3CCN(C(C)=O)CC3)CC2c2ccc(Cl)c(Cl)c2)cc1 | Homo sapiens | CHEMBL3707767 | cell-based format |
| CHEMBL3642161 |  |
IC50 | = | 160.0 | nM | 592.57 | CC(=O)N1CCC(C(=O)N2CC[C@@H](N(C)C(=O)c3ccc(-c4ccccc4)cc3)C(c3ccc(Cl)c(Cl)c3)C2)CC1 | Homo sapiens | CHEMBL3707767 | cell-based format |