Q9UEW8 | STK39_HUMAN | STE20/SPS1-related proline-alanine-rich protein kinase (STK39)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 63~337 | |
| PF12202 | OSR1_C - Oxidative-stress-responsive kinase 1 C-terminal domain | 452~509 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 14.4 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328622 | single protein format |
| CHEMBL5433617 |  |
IC50 | = | 35.0 | nM | 299.36 | Cn1cncc1C1=CN(c2ncnc3[nH]cnc23)CCS1 | Homo sapiens | CHEMBL5373870 | single protein format |
| CHEMBL4792789 |  |
IC50 | = | 50.0 | nM | 484.73 | O=C(Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1)c1cccc(O)c1O | Homo sapiens | CHEMBL4727716 | single protein format |
| CHEMBL4762099 |  |
IC50 | = | 110.0 | nM | 513.73 | O=C(Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1)c1cc([N+](=O)[O-])ccc1O | Homo sapiens | CHEMBL4727716 | single protein format |
| CHEMBL4759888 |  |
IC50 | = | 240.0 | nM | 484.73 | O=C(Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1)c1c(O)cccc1O | Homo sapiens | CHEMBL4727716 | single protein format |
| CHEMBL4797256 |  |
IC50 | = | 260.0 | nM | 537.62 | O=C(Nc1ccc(Oc2ccc3ccccc3c2Br)c(Cl)c1)c1cc(Cl)cc(Cl)c1O | Homo sapiens | CHEMBL4727716 | single protein format |
| CHEMBL4751500 |  |
IC50 | = | 650.0 | nM | 440.67 | O=C(Nc1ccc(Oc2cc(O)cc(O)c2)c(Cl)c1)c1cc(Cl)cc(Cl)c1O | Homo sapiens | CHEMBL4727716 | single protein format |
| CHEMBL4759820 |  |
IC50 | = | 1000.0 | nM | 476.67 | O=C(Nc1ccc(Oc2cccc(C(F)(F)F)c2)c(Cl)c1)c1cc(Cl)cc(Cl)c1O | Homo sapiens | CHEMBL4727716 | single protein format |