Q9UBY0 | SL9A2_HUMAN | Sodium/hydrogen exchanger 2 (SLC9A2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00999 | Na_H_Exchanger - Sodium/hydrogen exchanger, transmembrane | 88~484 | |
| PF16644 | NEXCaM_BD - Regulatory region of Na+/H+ exchanger NHE binds to calmodulin | 575~684 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3900457 |  |
IC50 | = | 70.0 | nM | 328.38 | C/C(=C\c1cccc(/C=C(\C)C(=O)NC(=N)N)c1)C(=O)N=C(N)N | Homo sapiens | CHEMBL3881462 | cell-based format |
| CHEMBL2170610 |  |
IC50 | = | 231.0 | nM | 356.35 | CC(=O)N1CCC(c2ccc(C(=O)NC(=N)N)cc2C(F)(F)F)CC1 | Homo sapiens | CHEMBL4882307 | single protein format |
| CHEMBL3974005 |  |
IC50 | = | 310.0 | nM | 324.4 | Cc1ccc(F)cc1[C@H]1C/C(=N\N=C(N)N)c2c(C)cccc2C1 | Homo sapiens | CHEMBL3882218 | single protein format |
| CHEMBL3957275 |  |
IC50 | = | 310.0 | nM | 310.38 | Cc1ccc(F)cc1[C@H]1C/C(=N\N=C(N)N)c2ccccc2C1 | Homo sapiens | CHEMBL3881462 | cell-based format |
| CHEMBL3900790 |  |
IC50 | = | 430.0 | nM | 324.4 | Cc1ccc(F)cc1[C@@H]1C/C(=N\N=C(N)N)c2c(C)cccc2C1 | Homo sapiens | CHEMBL3882218 | single protein format |
| CHEMBL3980085 |  |
IC50 | = | 430.0 | nM | 310.38 | Cc1ccc(F)cc1[C@@H]1C/C(=N\N=C(N)N)c2ccccc2C1 | Homo sapiens | CHEMBL3881462 | cell-based format |