Q9UBS5 | GABR1_HUMAN | Gamma-aminobutyric acid type B receptor subunit 1 (GABBR1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00003 | 7tm_3 - 7 transmembrane sweet-taste receptor of 3 GCPR | 588~856 | |
| PF00084 | Sushi - Sushi repeat (SCR repeat) | 119~157 | |
| PF01094 | ANF_receptor - Receptor family ligand binding region | 188~544 |
3D structures mapped by conservation among orthologs
[ Domain: "Periplasmic binding protein-like I" // ANF_receptor_2nd ]
[ Domain: "Periplasmic binding protein-like I" // ANF_receptor_2nd_1 ]
[ Domain: "Complement control module/SCR domain" // Sushi_3 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2391908 |  |
IC50 | = | 6.4 | nM | 444.77 | C[C@H](NC[C@H](O)CP(=O)(O)CC1CCCCC1)c1ccc(Cl)c(Cl)c1.Cl | Homo sapiens | CHEMBL2395266 | cell-based format |
| CHEMBL2391908 | |
Ki | = | 2.9 | nM | 444.77 | C[C@H](NC[C@H](O)CP(=O)(O)CC1CCCCC1)c1ccc(Cl)c(Cl)c1.Cl | Homo sapiens | CHEMBL2395266 | cell-based format |