Q9UBS0 | KS6B2_HUMAN | Ribosomal protein S6 kinase beta-2 (RPS6KB2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 67~328 | |
| PF00433 | Pkinase_C - Protein kinase C terminal domain | 349~389 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 2.35 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328540 | single protein format |
| CHEMBL426445 |  |
IC50 | = | 40.0 | nM | 388.47 | O=C(O)c1ccc2cc3nc(-c4cccs4)c(-c4cccs4)nc3cc2c1 | Homo sapiens | CHEMBL830066 | single protein format |
| CHEMBL192909 |  |
IC50 | = | 640.0 | nM | 460.54 | O=C(O)Cc1csc(-c2nc3cc4ccccc4cc3nc2-c2cc(CC(=O)O)cs2)c1 | Homo sapiens | CHEMBL830066 | single protein format |
| CHEMBL190057 |  |
IC50 | = | 820.0 | nM | 516.64 | O=C(O)CCCc1ccc(-c2nc3cc4ccccc4cc3nc2-c2ccc(CCCC(=O)O)s2)s1 | Homo sapiens | CHEMBL830066 | single protein format |
| CHEMBL366201 |  |
IC50 | = | 870.0 | nM | 488.59 | O=C(O)CCc1ccc(-c2nc3cc4ccccc4cc3nc2-c2ccc(CCC(=O)O)s2)s1 | Homo sapiens | CHEMBL830066 | single protein format |
| CHEMBL193232 |  |
IC50 | = | 950.0 | nM | 396.45 | O=C(O)C1COc2cc3nc(-c4cccs4)c(-c4cccs4)nc3cc2O1 | Homo sapiens | CHEMBL830066 | single protein format |