Q9UBP0 | SPAST_HUMAN | Spastin (SPAST)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00004 | AAA | 378–507 | |
| PF09336 | Vps4_C | 578–612 | |
| PF17862 | AAA_lid_3 | 534–567 |
3D structures mapped by conservation among orthologs
[ Domain: "AAA+ ATPase lid domain" // Vps4_C_C ]
[ Domain: "MIT domain" // MIT ]
[ Domain: "P-loop containing nucleoside triphosphate hydrolases" // Sigma54_activat ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5190401 |  |
IC50 | = | 99.0 | nM | 382.52 | CC(C)[C@@H]1CN(c2nc(Nc3cc(C(C)(C)C)[nH]n3)c3cc[nH]c3n2)CCN1 | Homo sapiens | CHEMBL5097625 | single protein format |