Q9UBM7 | DHCR7_HUMAN | 7-dehydrocholesterol reductase (DHCR7)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF01222 | ERG4_ERG24 - Ergosterol biosynthesis ERG4/ERG24 family | 92~475 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5281526 |  |
IC50 | = | 0.1 | nM | 412.6 | Cc1ccc(-c2ccc(S(=O)(=O)N3CCC(N4CCC(C)CC4)CC3)cc2)cc1 | Homo sapiens | CHEMBL5226846 | single protein format |
| CHEMBL2172347 |  |
IC50 | = | 2.3 | nM | 317.82 | COc1cc2c(cc1O)CCN(CCc1ccc(Cl)cc1)C2 | Homo sapiens | CHEMBL2175827 | cell-based format |
| CHEMBL5284923 |  |
IC50 | = | 30.0 | nM | 380.55 | CC1CCN(C2CCN(S(=O)(=O)c3ccc(OC(C)C)cc3)CC2)CC1 | Homo sapiens | CHEMBL5226846 | single protein format |
| CHEMBL2172349 |  |
IC50 | = | 120.0 | nM | 313.4 | COc1cccc(CCN2CCc3cc(O)c(OC)cc3C2)c1 | Homo sapiens | CHEMBL2175827 | cell-based format |
| CHEMBL2172263 |  |
IC50 | = | 500.0 | nM | 482.99 | O=C(O)c1ccc(CCN2CCN(C/C=C/c3ccc(Cl)cc3)CC2)cc1.O=S(=O)(O)O | Homo sapiens | CHEMBL2175827 | cell-based format |