Q9UBE8 | NLK_HUMAN | Serine/threonine-protein kinase NLK (NLK)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 141~427 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5276374 |  |
IC50 | = | 41.0 | nM | 453.54 | C=CC(=O)N1CCC([C@@H]2CCNc3c(C(N)=O)c(-c4cc(OC)c(C)c(OC)c4)nn32)CC1 | Homo sapiens | CHEMBL5251912 | single protein format |
| CHEMBL388978 |  |
IC50 | = | 77.8 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328533 | single protein format |
| CHEMBL5090394 |  |
IC50 | = | 250.0 | nM | 496.93 | CNc1ncc2cc(-c3ccc(-c4ncccc4F)cc3Cl)c(=O)n(C[C@H]3OC[C@H](N)CO3)c2n1 | Homo sapiens | CHEMBL5151385 | single protein format |
| CHEMBL4517408 |  |
IC50 | = | 336.0 | nM | 419.53 | COc1cc(-c2cncc(-c3ccc(N4CCNCC4)cc3)c2C)cc(OC)c1OC | Homo sapiens | CHEMBL4626197 | single protein format |
| CHEMBL10 |  |
IC50 | < | 1000.0 | nM | 377.44 | C[S+]([O-])c1ccc(-c2nc(-c3ccc(F)cc3)c(-c3ccncc3)[nH]2)cc1 | Homo sapiens | CHEMBL4602945 | single protein format |