Q9NZN5 | ARHGC_HUMAN | Rho guanine nucleotide exchange factor 12 (ARHGEF12)

Helixβ‑strandTurn secondary structure

Pfam Domain Table

AccessionDomainRangeColor
PF00595PDZ75–145
PF00621RhoGEF791–975
PF09128RGS-like368–558
PF17838PH_161005–1129

 3D structures mapped by conservation among orthologs

[ Domain: "PH domain-like" // PH_13_1 ]

 PyMOL session

[ Domain: "PDZ domain" // PDZ ]

 PyMOL session

[ Domain: "DBL homology domain (DH-domain)" // RhoGEF ]

 PyMOL session


 [ Alpha Fold Model ] (go)



 Known binders annotated in ChEMBL

 IC50 CSV
Only the first 20 rows are shown.
molecule_chembl_idstructureassay_typerelation valueunitmol_wtsmilesorganism assay_chembl_idbao_label
CHEMBL485210 IC50 = 1000.0 nM 384.44 Cc1cccc(COc2cccc(/C=C3\C(=O)NN(c4ccccc4)C3=O)c2)c1 Homo sapiens CHEMBL4419711 single protein format