Q9NZN5 | ARHGC_HUMAN | Rho guanine nucleotide exchange factor 12 (ARHGEF12)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00595 | PDZ - PDZ domain | 75~145 | |
| PF00621 | RhoGEF - RhoGEF domain | 791~975 | |
| PF09128 | RGS-like - Regulator of G protein signalling-like domain | 368~558 | |
| PF17838 | PH_16 - PH domain | 1005~1129 |
3D structures mapped by conservation among orthologs
[ Domain: "PH domain-like" // PH_13_1 ]
[ Domain: "PDZ domain" // PDZ ]
[ Domain: "DBL homology domain (DH-domain)" // RhoGEF ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL485210 |  |
IC50 | = | 1000.0 | nM | 384.44 | Cc1cccc(COc2cccc(/C=C3\C(=O)NN(c4ccccc4)C3=O)c2)c1 | Homo sapiens | CHEMBL4419711 | single protein format |