Q9NZ42 | PEN2_HUMAN | Gamma-secretase subunit PEN-2 (PSENEN)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF10251 | PEN-2 - Presenilin enhancer-2 subunit of gamma secretase | 7~99 |
3D structures mapped by conservation among orthologs
[ Domain: "Gamma-secretase subunit PEN-2" // PEN-2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL177969 |  |
IC50 | = | 50.0 | nM | 446.49 | C[C@H](NC(=O)Cc1cc(F)cc(F)c1)C(=O)N[C@@H](Cc1ccccc1)C(=O)OC(C)(C)C | Homo sapiens | CHEMBL676872 | single protein format |