Q9NYV8 | T2R14_HUMAN | Taste receptor type 2 member 14 (TAS2R14)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF05296 | TAS2R - Taste receptor protein (TAS2R) | 1~298 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL3895068 |  |
IC50 | = | 14.0 | nM | 401.53 | Cc1ccc(S(=O)(=O)N(Cc2ccccc2)CC2CCC(C(=O)O)CC2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3909546 |  |
IC50 | = | 36.0 | nM | 431.55 | COc1cccc(CN(CC2CCC(C(=O)O)CC2)S(=O)(=O)c2ccc(C)cc2)c1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3907785 |  |
IC50 | = | 54.0 | nM | 413.47 | Cc1ccc(S(=O)(=O)N(Cc2ccc(F)cc2)Cc2ccc(C(=O)O)cc2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3930803 |  |
IC50 | = | 83.0 | nM | 419.52 | Cc1ccc(S(=O)(=O)N(Cc2ccc(F)cc2)CC2CCC(C(=O)O)CC2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3905445 |  |
IC50 | = | 92.0 | nM | 435.52 | COc1ccc(S(=O)(=O)N(Cc2ccc(F)cc2)CC2CCC(C(=O)O)CC2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3904387 |  |
IC50 | = | 109.0 | nM | 415.56 | Cc1ccc(CN(CC2CCC(C(=O)O)CC2)S(=O)(=O)c2ccc(C)cc2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3901989 |  |
IC50 | = | 188.0 | nM | 427.48 | COc1cccc(CN(Cc2ccc(C(=O)O)cc2)S(=O)(=O)c2ccc(O)cc2)c1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3092287 |  |
IC50 | = | 200.0 | nM | 411.48 | COc1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(C(=O)O)cc2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3946036 |  |
IC50 | = | 240.0 | nM | 405.49 | O=C(O)C1CCC(CN(Cc2ccc(F)cc2)S(=O)(=O)c2ccccc2)CC1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL1401915 |  |
IC50 | = | 264.0 | nM | 389.39 | Cn1c(=O)c2cc(S(=O)(=O)Nc3ccc4c(c3)OCO4)ccc2n(C)c1=O | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3962122 |  |
IC50 | = | 292.0 | nM | 363.44 | Cc1nc(SCC(=O)N2CCCCC2)c2c(=O)n(C)c(=O)n(C)c2n1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3917592 |  |
IC50 | = | 334.0 | nM | 472.61 | CCOC(=O)C1CCC(CN(Cc2ccccc2)S(=O)(=O)c2ccc(NC(C)=O)cc2)CC1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3972175 |  |
IC50 | = | 342.0 | nM | 411.52 | O=C(O)C1CCC(CN(Cc2ccc(F)cc2)S(=O)(=O)c2cccs2)CC1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3954153 |  |
IC50 | = | 345.0 | nM | 411.48 | COc1cccc(CN(Cc2ccc(C(=O)O)cc2)S(=O)(=O)c2ccccc2)c1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL1082389 |  |
IC50 | = | 394.0 | nM | 415.9 | O=C(O)c1ccc(CN(Cc2ccccc2)S(=O)(=O)c2ccc(Cl)cc2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3892321 |  |
IC50 | = | 406.0 | nM | 399.44 | O=C(O)c1ccc(CN(Cc2cccc(F)c2)S(=O)(=O)c2ccccc2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3907807 |  |
IC50 | = | 429.0 | nM | 399.44 | O=C(O)c1ccc(CN(Cc2ccccc2F)S(=O)(=O)c2ccccc2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3976457 |  |
IC50 | = | 459.0 | nM | 415.44 | O=C(O)c1ccc(CN(Cc2cccc(F)c2)S(=O)(=O)c2ccc(O)cc2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3908011 |  |
IC50 | = | 499.0 | nM | 322.35 | N#C/C(=C\c1ccco1)C(=O)Nc1nnc(-c2ccccc2)s1 | Homo sapiens | CHEMBL3887148 | single protein format |
| CHEMBL3982886 |  |
IC50 | = | 499.0 | nM | 426.54 | Cc1ccc(S(=O)(=O)N(Cc2ccc(C#N)cc2)CC2CCC(C(=O)O)CC2)cc1 | Homo sapiens | CHEMBL3887148 | single protein format |