Q9NY91 | SC5A4_HUMAN | Solute carrier family 5 member 4 (SLC5A4)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00474 | SSF - Sodium:solute symporter family | 58~492 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1770248 |  |
IC50 | = | 0.877 | nM | 436.89 | CCOc1ccc(Cc2cc([C@]34OC[C@](CO)(O3)[C@@H](O)[C@H](O)[C@H]4O)ccc2Cl)cc1 | Homo sapiens | CHEMBL1772493 | cell-based format |
| CHEMBL1770246 |  |
IC50 | = | 0.882 | nM | 422.86 | COc1ccc(Cc2cc([C@]34OC[C@](CO)(O3)[C@@H](O)[C@H](O)[C@H]4O)ccc2Cl)cc1 | Homo sapiens | CHEMBL1772493 | cell-based format |
| CHEMBL1770244 |  |
IC50 | = | 1.07 | nM | 402.44 | COc1ccc(Cc2cc([C@]34OC[C@](CO)(O3)[C@@H](O)[C@H](O)[C@H]4O)ccc2C)cc1 | Homo sapiens | CHEMBL1772493 | cell-based format |
| CHEMBL1770245 |  |
IC50 | = | 1.11 | nM | 416.47 | CCOc1ccc(Cc2cc([C@]34OC[C@](CO)(O3)[C@@H](O)[C@H](O)[C@H]4O)ccc2C)cc1 | Homo sapiens | CHEMBL1772493 | cell-based format |
| CHEMBL429910 |  |
IC50 | = | 1.35 | nM | 408.88 | CCOc1ccc(Cc2cc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)ccc2Cl)cc1 | Homo sapiens | CHEMBL1780754 | cell-based format |
| CHEMBL270766 |  |
IC50 | = | 4.8 | nM | 376.41 | COc1ccc(Cc2ccccc2O[C@@H]2O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 | Homo sapiens | CHEMBL1821169 | cell-based format |
| CHEMBL1090058 |  |
IC50 | = | 6.98 | nM | 386.44 | COc1ccc(Cc2cc([C@@H]3OC4(COC4)[C@@H](O)[C@H](O)[C@H]3O)ccc2C)cc1 | Homo sapiens | CHEMBL1772493 | cell-based format |
| CHEMBL1819489 |  |
IC50 | = | 11.0 | nM | 384.47 | OC[C@H]1C[C@@H](Oc2ccccc2Cc2ccc(C3CC3)cc2)[C@H](O)[C@@H](O)[C@@H]1O | Homo sapiens | CHEMBL1821169 | cell-based format |
| CHEMBL245067 |  |
IC50 | = | 16.0 | nM | 436.41 | O=C(CCc1ccc(O)cc1)c1c(O)cc(O)cc1O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O | Homo sapiens | CHEMBL1821169 | cell-based format |
| CHEMBL1819492 |  |
IC50 | = | 19.0 | nM | 390.5 | CSc1ccc(Cc2ccccc2O[C@@H]2C[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 | Homo sapiens | CHEMBL1821169 | cell-based format |
| CHEMBL1819486 |  |
IC50 | = | 28.0 | nM | 372.46 | CCc1ccc(Cc2ccccc2O[C@@H]2C[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 | Homo sapiens | CHEMBL1821169 | cell-based format |
| CHEMBL1819490 |  |
IC50 | = | 29.0 | nM | 370.45 | C=Cc1ccc(Cc2ccccc2O[C@@H]2C[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 | Homo sapiens | CHEMBL1821169 | cell-based format |
| CHEMBL1819491 |  |
IC50 | = | 42.0 | nM | 374.43 | COc1ccc(Cc2ccccc2O[C@@H]2C[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 | Homo sapiens | CHEMBL1821169 | cell-based format |
| CHEMBL1770247 |  |
IC50 | = | 43.1 | nM | 422.86 | COc1ccc(Cc2cc([C@]34OC[C@](CO)(O3)[C@@H](O)[C@H](O)[C@@H]4O)ccc2Cl)cc1 | Homo sapiens | CHEMBL1772493 | cell-based format |
| CHEMBL1819485 |  |
IC50 | = | 59.0 | nM | 358.43 | Cc1ccc(Cc2ccccc2O[C@@H]2C[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O)cc1 | Homo sapiens | CHEMBL1821169 | cell-based format |
| CHEMBL1778657 |  |
IC50 | = | 59.5 | nM | 414.5 | CC/C=C/COc1ccc(Cc2cccc([C@@H]3O[C@H](CO)[C@@H](O)[C@H](O)[C@H]3O)c2)cc1 | Homo sapiens | CHEMBL1780754 | cell-based format |
| CHEMBL1778794 |  |
IC50 | = | 81.9 | nM | 428.53 | OC[C@H]1O[C@@H](c2ccc3c(c2)Cc2ccc(cc2)OCCCCCC3)[C@H](O)[C@@H](O)[C@@H]1O | Homo sapiens | CHEMBL1780754 | cell-based format |
| CHEMBL1778658 |  |
IC50 | = | 89.6 | nM | 426.51 | OC[C@H]1O[C@@H](c2ccc3c(c2)Cc2ccc(cc2)OC/C=C/CCC3)[C@H](O)[C@@H](O)[C@@H]1O | Homo sapiens | CHEMBL1780754 | cell-based format |
| CHEMBL1770249 |  |
IC50 | = | 89.9 | nM | 436.89 | CCOc1ccc(Cc2cc([C@]34OC[C@](CO)(O3)[C@@H](O)[C@H](O)[C@@H]4O)ccc2Cl)cc1 | Homo sapiens | CHEMBL1772493 | cell-based format |
| CHEMBL1778795 |  |
IC50 | = | 99.7 | nM | 442.55 | OC[C@H]1O[C@@H](c2ccc3c(c2)Cc2ccc(cc2)OCCCCCCC3)[C@H](O)[C@@H](O)[C@@H]1O | Homo sapiens | CHEMBL1780754 | cell-based format |