Q9NVM4 | ANM7_HUMAN | Protein arginine N-methyltransferase 7 (PRMT7)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF06325 | PrmA - Ribosomal protein L11 methyltransferase (PrmA) | 65~141 | |
| PF22528 | PRMT_C - Arginine methyltransferase oligomerization subdomain | 176~349 | |
| PF22528 | PRMT_C - Arginine methyltransferase oligomerization subdomain | 514~688 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5185202 |  |
IC50 | < | 2.5 | nM | 555.1 | Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCCCCNCc2cccc(-c3ccc(Cl)cc3)c2)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL5138252 | single protein format |
| CHEMBL5303356 |  |
IC50 | = | 77.0 | nM | 561.62 | Cc1ccc(S(=O)(=O)O)cc1.Cn1cc(Nc2nccc(N3CC4CCC(C3)N4C(=O)[C@@H]3CC3(F)F)n2)cn1 | Homo sapiens | CHEMBL5446214 | single protein format |
| CHEMBL418052 |  |
IC50 | = | 110.0 | nM | 384.42 | Nc1ncnc2c1ncn2[C@@H]1O[C@H](CSCC[C@H](N)C(=O)O)[C@@H](O)[C@H]1O | Homo sapiens | CHEMBL4684521 | single protein format |
| CHEMBL5408585 |  |
IC50 | = | 540.0 | nM | 594.59 | COC(=O)c1cc(O)c2cc(NC(=O)NCCNC(=N)NC[C@H]3O[C@@H](n4cnc5c(N)ncnc54)[C@H](O)[C@@H]3O)ccc2c1 | Homo sapiens | CHEMBL5366083 | single protein format |