Q9NR48 | ASH1L_HUMAN | Histone-lysine N-methyltransferase ASH1L (ASH1L)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00439 | Bromodomain | 2461–2535 | |
| PF00856 | SET | 2156–2261 | |
| PF01426 | BAH | 2663–2797 | |
| PF17907 | AWS | 2103–2141 | |
| PF20826 | PHD_5 | 2583–2628 |
3D structures mapped by conservation among orthologs
[ Domain: "SET domain-like" // SET ]
[ Domain: "Bromodomain" // Bromodomain ]
[ Domain: "Zn3Cys9 preSET domain-related" // AWS ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5410484 |  |
IC50 | = | 790.0 | nM | 592.71 | CN1CC(C(=O)NCc2ccc3c(-c4cccc(C(N)=S)c4)cn(C4CCC(S(=O)(=O)C(F)(F)F)CC4)c3c2)C1 | Homo sapiens | CHEMBL5380967 | assay format |