Q9NQV7 | PRDM9_HUMAN | Histone-lysine N-methyltransferase PRDM9 (PRDM9)
Helixβ‑strandTurn secondary structure
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00096 | zf-C2H2 | 552–574 | |
| PF00096 | zf-C2H2 | 580–602 | |
| PF00096 | zf-C2H2 | 608–630 | |
| PF00096 | zf-C2H2 | 636–658 | |
| PF00096 | zf-C2H2 | 664–686 | |
| PF00096 | zf-C2H2 | 692–714 | |
| PF00096 | zf-C2H2 | 720–742 | |
| PF00096 | zf-C2H2 | 748–770 | |
| PF00096 | zf-C2H2 | 776–798 | |
| PF00096 | zf-C2H2 | 804–826 | |
| PF00096 | zf-C2H2 | 832–854 | |
| PF00096 | zf-C2H2 | 860–882 | |
| PF01352 | KRAB | 28–62 | |
| PF09514 | SSXRD | 171–201 | |
| PF21225 | zf-C2H2_5 | 387–408 | |
| PF21549 | PRDM2_PR | 247–367 |
3D structures mapped by conservation among orthologs
[ Domain: "SET domain-like" // SET_4 ]
[ Domain: "beta-beta-alpha zinc fingers" // zf-C2H2 ]
[ Domain: "beta-beta-alpha zinc fingers" // zf-C2H2_1 ]
[ Domain: "beta-beta-alpha zinc fingers" // zf-C2H2_4 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4791017 |  |
IC50 | = | 800.0 | nM | 464.57 | COc1cc(OC)cc(-c2noc(N3CCN(C)C4(CCN(c5ccnc(C)c5)CC4)C3)n2)c1 | Homo sapiens | CHEMBL5210291 | cell-based format |