Q9NQR1 | KMT5A_HUMAN | N-lysine methyltransferase KMT5A (KMT5A)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00856 | SET - SET domain | 268~378 |
3D structures mapped by conservation among orthologs
[ Domain: "SET domain-like" // SET ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL337173 |  |
IC50 | = | 210.0 | nM | 321.76 | O=C1C(Cl)=C(NCCN2CCOCC2)C(=O)c2ncccc21 | Homo sapiens | CHEMBL3420965 | single protein format |
| CHEMBL3414625 |  |
IC50 | = | 500.0 | nM | 284.34 | Cc1ccc(/N=C2\CC(=O)c3sc(C)nc3C2=O)cc1 | Homo sapiens | CHEMBL3420965 | single protein format |
| CHEMBL290904 |  |
IC50 | = | 500.0 | nM | 284.34 | Cc1ccc(NC2=CC(=O)c3sc(C)nc3C2=O)cc1 | Homo sapiens | CHEMBL4309996 | single protein format |
| CHEMBL580421 |  |
IC50 | = | 700.0 | nM | 241.25 | CC1(C)C(=O)N=C2C1=C(O)C(=O)c1ccccc12 | Homo sapiens | CHEMBL3420965 | single protein format |
| CHEMBL4791952 |  |
IC50 | = | 804.0 | nM | 385.47 | C=CC(=O)NCCCNc1nc(N2CCCC2)nc2cc(OC)c(OC)cc12 | Homo sapiens | CHEMBL4673852 | assay format |