Q9NPC2 | KCNK9_HUMAN | Potassium channel subfamily K member 9 (KCNK9)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF07885 | Ion_trans_2 - Ion channel | 77~132 | |
| PF07885 | Ion_trans_2 - Ion channel | 170~243 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL2324344 |  |
IC50 | = | 35.0 | nM | 468.6 | CCCC(=O)C1CCN(c2ncnc3c2CN(C(=O)c2ccc(-c4ccccc4)cc2)CC3)CC1 | Homo sapiens | CHEMBL2327430 | single protein format |
| CHEMBL3183497 |  |
IC50 | = | 66.0 | nM | 390.44 | CCOc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL3182699 |  |
IC50 | = | 110.0 | nM | 458.44 | CC(C)Oc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC(F)(F)F)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL3185736 |  |
IC50 | = | 150.0 | nM | 344.41 | Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(C)c3)c2)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL3182449 |  |
IC50 | = | 300.0 | nM | 428.41 | CCOc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2C(F)(F)F)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL148342 |  |
IC50 | = | 318.0 | nM | 500.55 | COc1ccc(CC(=O)NCc2ccccc2-c2ccccc2C(=O)NCc2ccc(F)cc2F)cc1 | Homo sapiens | CHEMBL4322157 | cell-based format |
| CHEMBL3182091 |  |
IC50 | = | 330.0 | nM | 336.42 | Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccs3)c2)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL1081188 |  |
IC50 | = | 390.0 | nM | 360.41 | COc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL3188749 |  |
IC50 | = | 410.0 | nM | 430.38 | COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC(F)(F)F)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL3187482 |  |
IC50 | = | 410.0 | nM | 374.44 | CCOc1ccccc1C(=O)Nc1cccc(NC(=O)c2cccc(C)c2)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL1557966 |  |
IC50 | = | 413.0 | nM | 289.4 | CC(C1CC2CCC1C2)n1c(S)nnc1-c1ccco1 | Homo sapiens | CHEMBL4322171 | cell-based format |
| CHEMBL1086899 |  |
IC50 | = | 480.0 | nM | 364.83 | Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(Cl)c3)c2)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL1310568 |  |
IC50 | = | 500.0 | nM | 330.39 | Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3)c2)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL3182551 |  |
IC50 | = | 600.0 | nM | 348.38 | Cc1cccc(C(=O)Nc2cccc(NC(=O)c3cccc(F)c3)c2)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL3182359 |  |
IC50 | = | 710.0 | nM | 376.41 | COc1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC)c1 | Homo sapiens | CHEMBL3367869 | cell-based format |
| CHEMBL3186000 |  |
IC50 | = | 730.0 | nM | 442.44 | CC(C)c1ccccc1C(=O)Nc1cccc(NC(=O)c2ccccc2OC(F)(F)F)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL3182725 |  |
IC50 | = | 750.0 | nM | 414.38 | Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3OC(F)(F)F)c2)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL4592278 |  |
IC50 | = | 950.0 | nM | 405.52 | CCCCS(=O)(=O)Nc1ccccc1C(=O)NC(CC)c1ccc(OC)nc1 | Homo sapiens | CHEMBL4322157 | cell-based format |
| CHEMBL3181939 |  |
IC50 | = | 960.0 | nM | 344.41 | Cc1cccc(C(=O)Nc2cccc(NC(=O)c3ccccc3C)c2)c1 | Homo sapiens | CHEMBL3367861 | cell-based format |
| CHEMBL3182777 |  |
IC50 | = | 970.0 | nM | 322.39 | O=C(Nc1cccc(NC(=O)c2cccs2)c1)c1ccccc1 | Homo sapiens | CHEMBL3367861 | cell-based format |