Q9NP59 | S40A1_HUMAN | Solute carrier family 40 member 1 (SLC40A1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF06963 | FPN1 - Ferroportin1 (FPN1) | 23~531 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4587045 |  |
IC50 | = | 16.0 | nM | 408.44 | O=C(NCc1ncccc1F)c1cnc(CCNCCc2nc3ccccc3[nH]2)o1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4462224 |  |
IC50 | = | 17.0 | nM | 420.45 | O=C(NCc1ncccc1F)c1cnc(C2CN(CCc3nc4ccccc4[nH]3)C2)o1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4442485 |  |
IC50 | = | 19.0 | nM | 426.43 | O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3cc(F)ccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4565338 |  |
IC50 | = | 19.0 | nM | 420.45 | O=C(NCc1ncccc1F)c1coc(C2CN(CCc3nc4ccccc4[nH]3)C2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4468502 |  |
IC50 | = | 21.0 | nM | 426.43 | O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(F)cccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4575243 |  |
IC50 | = | 23.0 | nM | 568.68 | O=C(NCc1ncccc1F)c1csc(CCN(CCc2nc3ccccc3[nH]2)CCc2nc3ccccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4581730 |  |
IC50 | = | 26.0 | nM | 442.88 | O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(Cl)cccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4470632 |  |
IC50 | = | 30.0 | nM | 568.33 | Cl.Cl.Cl.O=C(NCc1ncccc1F)c1nc(CCNCCc2nc3ccccc3[nH]2)sc1Cl | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4456285 |  |
IC50 | = | 31.0 | nM | 424.89 | O=C(NCc1ncccc1Cl)c1coc(CCNCCc2nc3ccccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4589376 |  |
IC50 | = | 34.0 | nM | 442.5 | O=C(NCc1ncccc1F)c1csc(CCNCCc2nc3c(F)cccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4441062 |  |
IC50 | = | 35.0 | nM | 461.38 | O=C(NCc1ncccc1Cl)c1nc(CCNCc2nc3ccccc3[nH]2)sc1Cl | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4459067 |  |
IC50 | = | 36.0 | nM | 394.41 | O=C(NCc1ncccc1F)c1coc(CNCCc2nc3ccccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4520569 |  |
IC50 | = | 38.0 | nM | 438.44 | O=C(NCc1ncccc1F)c1coc(C2CN(CCc3nc4c(F)cccc4[nH]3)C2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4445738 |  |
IC50 | = | 38.0 | nM | 444.42 | O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(F)c(F)ccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4473202 |  |
IC50 | = | 38.0 | nM | 470.96 | O=C(NCc1ncccc1F)c1nc(C2CN(CCc3nc4ccccc4[nH]3)C2)sc1Cl | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4573733 |  |
IC50 | = | 41.0 | nM | 432.55 | O=C(NC1CCc2cccnc21)c1csc(CCNCCc2nc3ccccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4539480 |  |
IC50 | = | 44.0 | nM | 424.51 | O=C(NCc1ncccc1F)c1csc(CCNCCc2nc3ccccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4579471 |  |
IC50 | = | 44.0 | nM | 444.42 | O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(F)cc(F)cc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4456611 |  |
IC50 | = | 46.0 | nM | 476.43 | O=C(NCc1ncccc1F)c1coc(CCNCCc2nc3c(C(F)(F)F)cccc3[nH]2)n1 | Homo sapiens | CHEMBL4419455 | assay format |
| CHEMBL4462521 |  |
IC50 | = | 47.0 | nM | 402.46 | O=C(NCc1ccccn1)c1coc(C2CN(CCc3nc4ccccc4[nH]3)C2)n1 | Homo sapiens | CHEMBL4419455 | assay format |