Q9HCN6 | GPVI_HUMAN | Platelet glycoprotein VI (GP6)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF13895 | Ig_2 - Immunoglobulin domain | 27~106 | |
| PF13927 | Ig_3 - Immunoglobulin domain | 113~180 |
3D structures mapped by conservation among orthologs
[ Domain: "Immunoglobulin/Fibronectin type III/E set domains/PapD-like" // Ig_2 ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL549359 |  |
IC50 | = | 21.0 | nM | 332.44 | C=C1C(=O)[C@@]23[C@H](O)C[C@@H]4C(C)(C)C(=O)CC[C@@]4(C)[C@@H]2CC[C@@H]1[C@H]3O | Homo sapiens | CHEMBL4687284 | tissue-based format |
| CHEMBL1235110 |  |
IC50 | = | 48.0 | nM | 340.43 | Cc1cccc(Nc2nc(N[C@@H]3CCCC[C@@H]3N)ncc2C(N)=O)c1 | Homo sapiens | CHEMBL4687291 | tissue-based format |
| CHEMBL1873475 |  |
IC50 | = | 120.0 | nM | 440.51 | C=CC(=O)N1CCC[C@@H](n2nc(-c3ccc(Oc4ccccc4)cc3)c3c(N)ncnc32)C1 | Homo sapiens | CHEMBL4687297 | tissue-based format |
| CHEMBL3936761 |  |
IC50 | = | 510.0 | nM | 471.56 | C=CC(=O)N1CCC([C@@H]2CCNc3c(C(N)=O)c(-c4ccc(Oc5ccccc5)cc4)nn32)CC1 | Homo sapiens | CHEMBL4687297 | tissue-based format |