Q9HC98 | NEK6_HUMAN | Serine/threonine-protein kinase Nek6 (NEK6)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 45~296 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1793896 |  |
IC50 | = | 336.0 | nM | 514.51 | C=Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCN(C)CC4)ccc3OC(F)(F)F)ncc1CC2 | Homo sapiens | CHEMBL1272702 | single protein format |
| CHEMBL3104851 |  |
IC50 | = | 520.0 | nM | 374.3 | Cc1c(O)c(O)c2c(c1C=O)[C@@H]1O[C@H](O2)c2c(C)c(O)c(O)c(O)c2C1=O | Homo sapiens | CHEMBL3108320 | single protein format |
| CHEMBL1271644 |  |
IC50 | = | 595.0 | nM | 488.47 | Cn1nc(C(N)=O)c2c1-c1nc(Nc3cc(N4CCNCC4)ccc3OC(F)(F)F)ncc1CC2 | Homo sapiens | CHEMBL1272702 | single protein format |