Q9HBY8 | SGK2_HUMAN | Serine/threonine-protein kinase Sgk2 (SGK2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 37~292 | |
| PF00433 | Pkinase_C - Protein kinase C terminal domain | 313~357 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 16.5 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328601 | single protein format |
| CHEMBL5082336 |  |
IC50 | = | 21.0 | nM | 425.86 | N#Cc1ccc(Cl)cc1S(=O)(=O)Nc1ccc(-c2ncc3c(N)n[nH]c3n2)cc1 | Homo sapiens | CHEMBL5043748 | single protein format |
| CHEMBL3092468 |  |
IC50 | = | 128.0 | nM | 418.84 | Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cc(Cl)ccc4F)cc3)cnc12 | Homo sapiens | CHEMBL3375445 | single protein format |
| CHEMBL3092460 |  |
IC50 | = | 924.0 | nM | 435.3 | Nc1n[nH]c2nc(-c3ccc(NS(=O)(=O)c4cccc(Cl)c4Cl)cc3)cnc12 | Homo sapiens | CHEMBL3375445 | single protein format |