Q9HBW0 | LPAR2_HUMAN | Lysophosphatidic acid receptor 2 (LPAR2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00001 | 7tm_1 - 7 transmembrane receptor (rhodopsin family) | 47~292 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL119116 |  |
IC50 | = | 6.6 | nM | 426.32 | CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1Cl | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL5283300 |  |
IC50 | = | 10.0 | nM | 291.35 | Cc1cccc(C2CC2C(=O)Nc2nc3ccccc3[nH]2)c1 | Homo sapiens | CHEMBL5242006 | single protein format |
| CHEMBL5266099 |  |
IC50 | = | 10.0 | nM | 345.32 | O=C(Nc1nc2cc(C(F)(F)F)ccc2[nH]1)C1CC1c1ccccc1 | Homo sapiens | CHEMBL5242006 | single protein format |
| CHEMBL5290275 |  |
IC50 | = | 10.0 | nM | 311.77 | O=C(Nc1nc2cc(Cl)ccc2[nH]1)C1CC1c1ccccc1 | Homo sapiens | CHEMBL5242006 | single protein format |
| CHEMBL5282947 |  |
IC50 | < | 10.0 | nM | 277.33 | O=C(Nc1nc2ccccc2[nH]1)C1CC1c1ccccc1 | Homo sapiens | CHEMBL5242006 | single protein format |
| CHEMBL5278054 |  |
IC50 | = | 10.0 | nM | 311.77 | O=C(Nc1nc2ccccc2[nH]1)C1CC1c1ccccc1Cl | Homo sapiens | CHEMBL5242006 | single protein format |
| CHEMBL119440 |  |
IC50 | = | 15.0 | nM | 385.49 | CCCCCCCCOc1c(C)cc(CNCCCP(=O)(O)O)cc1C | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL441826 |  |
IC50 | = | 18.0 | nM | 494.41 | CCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL332667 |  |
IC50 | = | 23.0 | nM | 515.22 | CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1Br | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL119256 |  |
IC50 | = | 26.0 | nM | 341.43 | CCCCCCCCc1ccc(CNCCCP(=O)(O)O)cc1 | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL331054 |  |
IC50 | = | 32.0 | nM | 371.46 | CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1C | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL118783 |  |
IC50 | = | 33.0 | nM | 452.33 | CCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL119354 |  |
IC50 | = | 36.0 | nM | 436.33 | CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Br | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL118860 |  |
IC50 | = | 40.0 | nM | 355.46 | CCCCCCCCCc1ccc(CNCCCP(=O)(O)O)cc1 | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL118815 |  |
IC50 | = | 42.0 | nM | 508.43 | CCCCCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL119413 |  |
IC50 | = | 55.0 | nM | 391.88 | CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1Cl | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL117715 |  |
IC50 | = | 57.0 | nM | 421.9 | CCCCCCCCOc1c(Cl)cc(CNCCCP(=O)(O)O)cc1OC | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL119873 |  |
IC50 | = | 59.0 | nM | 375.42 | CCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1F | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL333335 |  |
IC50 | = | 74.0 | nM | 371.46 | CCCCCCCCCOc1ccc(CNCCCP(=O)(O)O)cc1 | Homo sapiens | CHEMBL807594 | cell-based format |
| CHEMBL117723 |  |
IC50 | = | 80.0 | nM | 466.35 | CCCCCCCCOc1c(Br)cc(CNCCCP(=O)(O)O)cc1OC | Homo sapiens | CHEMBL807594 | cell-based format |