Q9H999 | PANK3_HUMAN | Pantothenate kinase 3 (PANK3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF03630 | Fumble - Fumble | 13~364 |
3D structures mapped by conservation among orthologs
[ Domain: "Ribonuclease H-like" // Fumble_C ]
[ Domain: "Ribonuclease H-like" // Fumble_N ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL5082138 |  |
IC50 | = | 0.4 | nM | 358.87 | CC(C)c1ccc(CC(=O)N2CCN(c3ccc(Cl)nn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL363699 |  |
IC50 | = | 0.7 | nM | 359.86 | CC(C)c1ccc(NC(=O)N2CCN(c3ccc(Cl)nn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5077276 |  |
IC50 | = | 1.0 | nM | 349.44 | CC(C)c1ccc(CC(=O)N2CCN(c3ccc(C#N)nn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5094733 |  |
IC50 | = | 1.8 | nM | 358.87 | CC(C)c1ccc(CC(=O)N2CCN(c3cnc(Cl)cn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5078496 |  |
IC50 | = | 4.0 | nM | 350.43 | CC(C)c1ccc(NC(=O)N2CCN(c3ccc(C#N)nn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5085732 |  |
IC50 | = | 10.0 | nM | 349.44 | CC(C)c1ccc(CC(=O)N2CCN(c3cnc(C#N)nc3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5082695 |  |
IC50 | = | 10.0 | nM | 351.41 | CC(C)c1ccc(OC(=O)N2CCN(c3ccc(C#N)nn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5093027 |  |
IC50 | = | 20.0 | nM | 369.43 | CC(C)c1ccc(NC(=O)N2CCN(c3ccc([N+](=O)[O-])cn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL3410246 |  |
IC50 | = | 25.0 | nM | 391.5 | CSc1cccc(NC(=O)CCc2c(C)nc3c4cccnc4nn3c2C)c1 | Homo sapiens | CHEMBL3413789 | single protein format |
| CHEMBL5075383 |  |
IC50 | = | 29.0 | nM | 350.43 | CC(C)c1ccc(NC(=O)N2CCN(c3cnc(C#N)cn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5092780 |  |
IC50 | = | 60.0 | nM | 362.48 | CC(C)(C)c1ccc(CC(=O)N2CCN(c3ccc(C#N)cn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5078248 |  |
IC50 | = | 60.0 | nM | 348.45 | CC(C)c1ccc(CC(=O)N2CCN(c3ccc(C#N)cn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL3410245 |  |
IC50 | = | 120.0 | nM | 381.5 | CC(C)c1ccc(NC(=O)CCc2nc(O)c3c4c(sc3n2)CCC4)cc1 | Homo sapiens | CHEMBL3413791 | single protein format |
| CHEMBL5088913 |  |
IC50 | = | 140.0 | nM | 350.43 | CC(C)c1ccc(NC(=O)N2CCN(c3nccc(C#N)n3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5088098 |  |
IC50 | = | 160.0 | nM | 404.31 | CC(C)c1ccc(NC(=O)N2CCN(c3ncc(Br)cn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5092773 |  |
IC50 | = | 170.0 | nM | 350.43 | CC(C)c1ccc(NC(=O)N2CCN(c3cnc(C#N)nc3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL3410244 |  |
IC50 | = | 180.0 | nM | 322.43 | CCS(=O)(=O)Nc1ccc(C(=O)NC2CC3CCC2C3)cc1 | Homo sapiens | CHEMBL3413791 | single protein format |
| CHEMBL5073319 |  |
IC50 | = | 200.0 | nM | 346.43 | N#Cc1ccc(N2CCN(C(=O)Cc3ccc(C4CC4)cc3)CC2)nc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5070550 |  |
IC50 | = | 220.0 | nM | 358.87 | CC(C)c1ccc(NC(=O)N2CCN(c3ccc(Cl)cn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |
| CHEMBL5076791 |  |
IC50 | = | 220.0 | nM | 403.32 | CC(C)c1ccc(NC(=O)N2CCN(c3ccc(Br)cn3)CC2)cc1 | Homo sapiens | CHEMBL5055302 | assay format |