Q9H4B7 | TBB1_HUMAN | Tubulin beta-1 chain (TUBB1)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00091 | Tubulin - Tubulin/FtsZ family, GTPase domain | 3~211 | |
| PF03953 | Tubulin_C - Tubulin C-terminal domain | 261~382 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL370250 |  |
IC50 | = | 120.0 | nM | 268.36 | COc1ccc(/C=C\c2cc(C)c(C)c(C)c2)cc1O | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL193716 |  |
IC50 | = | 130.0 | nM | 330.38 | COc1ccc(/C=C(/C)c2cc(OC)c(OC)c(OC)c2)cc1O | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL195572 |  |
IC50 | = | 130.0 | nM | 344.41 | CC/C(=C/c1ccc(OC)c(O)c1)c1cc(OC)c(OC)c(OC)c1 | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL67 |  |
IC50 | = | 180.0 | nM | 316.35 | COc1ccc(/C=C\c2cc(OC)c(OC)c(OC)c2)cc1O | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL47426 |  |
IC50 | = | 200.0 | nM | 300.35 | COc1ccc(/C=C\c2cc(OC)c(OC)c(OC)c2)cc1 | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL195840 |  |
IC50 | = | 450.0 | nM | 344.36 | COc1ccc(/C=C/C(=O)c2ccc(OC)c(OC)c2OC)cc1O | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL9859 |  |
IC50 | = | 460.0 | nM | 358.39 | COc1ccc(/C=C(\C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL371839 |  |
IC50 | = | 470.0 | nM | 376.38 | CO/C(=C\c1ccc(OC)c(F)c1)C(=O)c1cc(OC)c(OC)c(OC)c1 | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL192739 |  |
IC50 | = | 500.0 | nM | 358.43 | CCOc1cc(/C=C\c2ccc(OC)c(O)c2)cc(OCC)c1OCC | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL364034 |  |
IC50 | = | 510.0 | nM | 374.39 | CO/C(=C\c1ccc(OC)c(O)c1)C(=O)c1cc(OC)c(OC)c(OC)c1 | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL150582 |  |
IC50 | = | 560.0 | nM | 332.35 | COc1ccc(OCc2cc(OC)c(OC)c(OC)c2)cc1C=O | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL9941 |  |
IC50 | = | 620.0 | nM | 344.36 | COc1ccc(/C=C/C(=O)c2cc(OC)c(OC)c(OC)c2)cc1O | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL192540 |  |
IC50 | = | 650.0 | nM | 252.36 | COc1ccc(/C=C\c2cc(C)c(C)c(C)c2)cc1 | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL426644 |  |
IC50 | = | 650.0 | nM | 360.38 | COc1ccc(/C=C(\C)C(=O)c2cc(OC)c(OC)c(OC)c2)cc1F | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL192056 |  |
IC50 | = | 700.0 | nM | 270.35 | COc1ccc(/C=C\c2cc(C)c(C)c(C)c2)cc1F | Homo sapiens | CHEMBL832453 | single protein format |
| CHEMBL363063 |  |
IC50 | = | 900.0 | nM | 355.39 | COc1ccc2c(C(=O)c3cc(OC)c(OC)c(OC)c3)c(C)[nH]c2c1 | Homo sapiens | CHEMBL876479 | single protein format |