Q9H2K8 | TAOK3_HUMAN | Serine/threonine-protein kinase TAO3 (TAOK3)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 28~277 |
3D structures mapped by conservation among orthologs
[ Domain: "Protein kinase" // Pkinase_Tyr ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 2.11 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328627 | single protein format |
| CHEMBL2334586 |  |
IC50 | = | 45.0 | nM | 332.41 | CC(C)(O)C#Cc1ccc2[nH]c3c(c2c1)-c1nc(N)ncc1CCC3 | Homo sapiens | CHEMBL5111449 | assay format |
| CHEMBL3716416 |  |
IC50 | = | 50.0 | nM | 440.47 | CCc1ccc(-c2ccc(C(=O)NCC(=O)NCc3ccccc3C(F)(F)F)cc2)cc1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3716741 |  |
IC50 | < | 50.0 | nM | 426.56 | CCc1ccc(-c2ccc(C(=O)NC(C)C(=O)NC3CCc4ccccc4C3)cc2)cc1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3717300 |  |
IC50 | < | 50.0 | nM | 412.53 | CCc1ccc(-c2ccc(C(=O)NCC(=O)NC3CCCc4ccccc43)cc2)cc1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3715148 |  |
IC50 | < | 50.0 | nM | 417.3 | O=C(COc1ccc(Br)cc1)NCC(=O)NC1CCCc2ccccc21 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3715887 |  |
IC50 | < | 50.0 | nM | 444.53 | O=C(COc1ccc(OCc2ccccc2)cc1)NCC(=O)NC1CCCc2ccccc21 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3717017 |  |
IC50 | < | 50.0 | nM | 394.52 | CCCCCOc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3716742 |  |
IC50 | = | 50.0 | nM | 408.48 | O=C(CC(NC(=O)c1ccccc1)c1ccccc1)NCC(=O)Nc1nccs1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3716774 |  |
IC50 | = | 50.0 | nM | 400.52 | CCc1ccc(-c2ccc(C(=O)NCC(=O)NC(CC)c3ccccc3)cc2)cc1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3717713 |  |
IC50 | = | 50.0 | nM | 359.43 | O=C(CNC(=O)c1ccc2ncccc2c1)NC1CCCc2ccccc21 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3715821 |  |
IC50 | < | 50.0 | nM | 408.54 | CCCCCCOc1ccc(C(=O)NCC(=O)NC2CCCc3ccccc32)cc1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3715942 |  |
IC50 | = | 50.0 | nM | 386.5 | CCc1ccc(-c2ccc(C(=O)NCC(=O)NC(C)c3ccccc3)cc2)cc1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3718940 |  |
IC50 | = | 50.0 | nM | 391.52 | O=C(CNC(=O)c1ccc(N2CCCCC2)cc1)NC1CCCc2ccccc21 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3715956 |  |
IC50 | = | 50.0 | nM | 386.5 | CCc1ccc(-c2ccc(C(=O)NCC(=O)NCc3ccccc3C)cc2)cc1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3717373 |  |
IC50 | = | 50.0 | nM | 399.49 | O=C(CNC(=O)Nc1ccc(-c2ccccc2)cc1)NC1CCCc2ccccc21 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3718164 |  |
IC50 | = | 50.0 | nM | 374.44 | O=C(CNC(=O)c1ccc(-n2ccnc2)cc1)NC1CCCc2ccccc21 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3717846 |  |
IC50 | < | 50.0 | nM | 489.56 | COc1ccc2nc(NC(=O)CNC(=O)CC(NC(=O)c3ccccc3)c3ccccc3)sc2n1 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3716849 |  |
IC50 | = | 50.0 | nM | 324.38 | O=C(CNC(=O)c1ccc(O)cc1)NC1CCCc2ccccc21 | Homo sapiens | CHEMBL3720850 | assay format |
| CHEMBL3716744 |  |
IC50 | = | 50.0 | nM | 394.52 | CCCCOc1ccc(C(=O)NC(C)C(=O)NC2CCc3ccccc3C2)cc1 | Homo sapiens | CHEMBL3720850 | assay format |