Q9H093 | NUAK2_HUMAN | NUAK family SNF1-like kinase 2 (NUAK2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00069 | Pkinase - Protein kinase domain | 53~303 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL388978 |  |
IC50 | = | 1.67 | nM | 466.54 | CN[C@@H]1C[C@H]2O[C@@](C)([C@@H]1OC)n1c3ccccc3c3c4c(c5c6ccccc6n2c5c31)C(=O)NC4 | Homo sapiens | CHEMBL4328607 | single protein format |
| CHEMBL4303523 |  |
IC50 | = | 100.0 | nM | 497.0 | CCC(=O)Nc1cccc(Oc2nc(Nc3ccc(N4CCN(C)CC4)cc3OC)ncc2Cl)c1 | Homo sapiens | CHEMBL5096589 | assay format |
| CHEMBL5199998 |  |
IC50 | = | 120.0 | nM | 373.43 | CC1(C)C(=O)N([C@H]2CCc3c(O)cccc32)c2nc(S(C)(=O)=O)ncc21 | Homo sapiens | CHEMBL5096575 | single protein format |
| CHEMBL5079149 |  |
IC50 | = | 900.0 | nM | 546.45 | NS(=O)(=O)c1ccc(CNc2nc(Nc3cccc(NC(=O)N4CCCC4)c3)ncc2Br)cc1 | Homo sapiens | CHEMBL5046613 | single protein format |