Q9GZV3 | SC5A7_HUMAN | High affinity choline transporter 1 (SLC5A7)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00474 | SSF - Sodium:solute symporter family | 43~442 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL1872483 |  |
IC50 | = | 240.0 | nM | 415.53 | COc1ccc(C(=O)NCc2cc(C(C)C)no2)cc1OC1CCN(C(C)C)CC1 | Homo sapiens | CHEMBL3404113 | cell-based format |
| CHEMBL3304438 |  |
IC50 | = | 270.0 | nM | 387.48 | COc1ccc(C(=O)NCc2cc(C(C)C)no2)cc1OC1CCN(C)CC1 | Homo sapiens | CHEMBL3404113 | cell-based format |
| CHEMBL3933906 |  |
IC50 | = | 270.0 | nM | 391.9 | CC(C)c1cc(CNC(=O)c2ccc(Cl)c(OC3CCN(C)CC3)c2)on1 | Homo sapiens | CHEMBL3860689 | cell-based format |
| CHEMBL3899143 |  |
IC50 | = | 467.0 | nM | 375.44 | CC(C)c1cc(CNC(=O)c2ccc(F)c(OC3CCN(C)CC3)c2)on1 | Homo sapiens | CHEMBL3860689 | cell-based format |
| CHEMBL1340914 |  |
IC50 | = | 600.0 | nM | 401.51 | CCc1cc(CNC(=O)c2ccc(OC)c(OC3CCN(C(C)C)CC3)c2)on1 | Homo sapiens | CHEMBL3404110 | cell-based format |
| CHEMBL3959257 |  |
IC50 | = | 640.0 | nM | 357.45 | CC(C)c1cc(CNC(=O)c2cccc(OC3CCN(C)CC3)c2)on1 | Homo sapiens | CHEMBL3860689 | cell-based format |
| CHEMBL3303792 |  |
IC50 | = | 760.0 | nM | 401.51 | COc1ccc(C(=O)NCc2cc(C(C)C)no2)cc1OCCN1CCCCC1 | Homo sapiens | CHEMBL3404113 | cell-based format |
| CHEMBL1887357 |  |
IC50 | = | 760.0 | nM | 417.58 | COc1ccc(C(=O)NCc2nc(C)c(C)s2)cc1OC1CCN(C(C)C)CC1 | Homo sapiens | CHEMBL3404110 | cell-based format |
| CHEMBL3182315 |  |
IC50 | = | 910.0 | nM | 428.58 | CCn1nc(C)c(CNC(=O)c2ccc(OC)c(OC3CCN(C(C)C)CC3)c2)c1C | Homo sapiens | CHEMBL3404114 | cell-based format |