Q9BZM2 | PA2GF_HUMAN | Group IIF secretory phospholipase A2 (PLA2G2F)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00068 | Phospholip_A2_1 - Phospholipase A2 | 22~131 |
3D structures mapped by conservation among orthologs
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL515637 |  |
IC50 | = | 50.0 | nM | 430.46 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990832 | single protein format |
| CHEMBL148649 |  |
IC50 | = | 90.0 | nM | 394.43 | CCc1c(C(=O)C(N)=O)c2c(OC(C)C(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990832 | single protein format |
| CHEMBL514705 |  |
IC50 | = | 90.0 | nM | 458.51 | CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990832 | single protein format |
| CHEMBL148674 |  |
IC50 | = | 130.0 | nM | 380.4 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990832 | single protein format |
| CHEMBL506485 |  |
IC50 | = | 290.0 | nM | 597.69 | CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990832 | single protein format |
| CHEMBL504813 |  |
IC50 | = | 550.0 | nM | 408.45 | CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccc2n1Cc1ccccc1 | Homo sapiens | CHEMBL990832 | single protein format |
| CHEMBL446349 |  |
IC50 | = | 550.0 | nM | 569.64 | CCc1c(C(=O)C(N)=O)c2c(OCC(=O)NS(=O)(=O)c3ccccc3)cc3ccccc3c2n1Cc1ccccc1 | Homo sapiens | CHEMBL990832 | single protein format |
| CHEMBL478820 |  |
IC50 | = | 970.0 | nM | 484.55 | CC(C)Cc1c(C(=O)C(N)=O)c2c(OCC(=O)O)cccn2c1Cc1ccccc1-c1ccccc1 | Homo sapiens | CHEMBL990832 | single protein format |