Q9BXF3 | CECR2_HUMAN | Cat eye syndrome critical region protein 2 (CECR2)
Pfam Domain Table
| Accession | Domain | Range | Color |
|---|---|---|---|
| PF00439 | Bromodomain - Bromodomain | 445~524 |
3D structures mapped by conservation among orthologs
[ Domain: "Bromodomain" // Bromodomain ]
[ Alpha Fold Model ] (go)
Known binders annotated in ChEMBL
Only the first 20 rows are shown.
| molecule_chembl_id | structure | assay_type | relation | value | unit | mol_wt | smiles | organism | assay_chembl_id | bao_label |
|---|---|---|---|---|---|---|---|---|---|---|
| CHEMBL4073178 |  |
IC50 | = | 16.0 | nM | 498.59 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4cccc(OC)c4)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4461619 |  |
IC50 | = | 30.0 | nM | 458.59 | CN(C)CCCOc1ccc(-c2cc(NCCCn3cccn3)nc(S(C)(=O)=O)n2)cc1 | Homo sapiens | CHEMBL4823119 | single protein format |
| CHEMBL4075584 |  |
IC50 | = | 44.0 | nM | 486.55 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4ccccc4F)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4076944 |  |
IC50 | = | 45.0 | nM | 458.52 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4ccco4)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4077439 |  |
IC50 | = | 45.0 | nM | 498.59 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4ccccc4OC)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4104121 |  |
IC50 | = | 46.0 | nM | 482.59 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-c4ccccc4C)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL3785432 |  |
IC50 | = | 47.0 | nM | 495.69 | CCCS(=O)(=O)c1nc(NC2CC2)cc(-c2ccc3c(ccn3C3CC(C)(C)NC(C)(C)C3)c2)n1 | Homo sapiens | CHEMBL3790854 | single protein format |
| CHEMBL4088221 |  |
IC50 | = | 52.0 | nM | 446.56 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C4CC4)nc(C)n3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4062038 |  |
IC50 | = | 55.0 | nM | 448.57 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C(C)(C)C)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4062597 |  |
IC50 | = | 59.0 | nM | 458.53 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(-n4cccn4)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4081975 |  |
IC50 | = | 71.0 | nM | 436.52 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(OC)nc(C)n3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL3133807 |  |
IC50 | = | 79.3 | nM | 404.45 | CCOC(=O)Nc1cc(-c2ccc(C)c(NS(C)(=O)=O)c2)nn2c(C)nnc12 | Homo sapiens | CHEMBL4650014 | single protein format |
| CHEMBL4093696 |  |
IC50 | = | 83.0 | nM | 432.53 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C4CC4)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4076384 |  |
IC50 | = | 93.0 | nM | 420.52 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C)nc(C)n3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4076381 |  |
IC50 | = | 130.0 | nM | 422.49 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(OC)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4460783 |  |
IC50 | = | 170.0 | nM | 321.38 | C=CCn1cc(-c2cccc(C(=O)N(C)C)c2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4425853 | single protein format |
| CHEMBL4077529 |  |
IC50 | = | 190.0 | nM | 432.57 | C=CCn1cc(C(=O)N(C)C2CCN([C@@H](C)c3ccccc3)CC2)c2cc(C)[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL3769507 |  |
IC50 | = | 195.6 | nM | 497.56 | CCn1cc(-c2cccc(C(F)(F)F)c2)c2sc(C(=N)NC3CCS(=O)(=O)CC3)cc2c1=O | Homo sapiens | CHEMBL4650014 | single protein format |
| CHEMBL4068293 |  |
IC50 | = | 200.0 | nM | 460.46 | C=CCn1cc(C(=O)N(C)C2CCN(c3cc(C(F)(F)F)ncn3)CC2)c2cc[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |
| CHEMBL4078864 |  |
IC50 | = | 200.0 | nM | 432.57 | C=CCn1cc(C(=O)N(C)C2CCN([C@H](C)c3ccccc3)CC2)c2cc(C)[nH]c2c1=O | Homo sapiens | CHEMBL4058265 | cell-based format |